头孢替唑母核
- 中文名称：
- 头孢替唑母核
- 中文别名：
- 头孢替唑母核
- 英文名称：
- Triazinate
- 英文别名：
- Ethanesulfonic acid, compd. with .α.-[2-chloro-4-(4,6-diamino-2,2-dimethyl-s-triazin-1(2H)-yl)-phenoxy]-N,N-dimethyl-m-toluamide;
Triazinate
- CAS No.：
- 41191-04-2
- 分 子 式：
-
C21H25ClN6O2.C2H6O3S
- 分 子 量：
- 539.054
- 精确分子量：
- 538.17700
- PSA：
- 172.29000
- InChI：
- The Key: HKPVIFTWECXNPY-UHFFFAOYSA-N3
- SDS：
- 查看
头孢替唑母核 物化性质
- 密度：
- 1.32g/cm3
- 沸点：
- 631.1ºC at 760 mmHg
- 闪点：
- 335.5ºC
- 折射率：
- 1.635
头孢替唑母核 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XS3650000
- CHEMICAL NAME :
- m-Toluamide,
alpha-(2-chloro-4-(4,6-diamino-2,2-dimethyl-s-triazin
e-1(2H)-yl)phenoxy)- N,N-dimethyl-, ethanesulfonate
- CAS REGISTRY NUMBER :
- 41191-04-2
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C21-H25-Cl-N6-O2.C2-H6-O3-S
- MOLECULAR WEIGHT :
- 539.11
- WISWESSER LINE NOTATION :
- T6N CN EN BHJ AR CG BO1R CVN1&1&& B1 B1 DZ FZ &WSQ2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 1355 mg/kg/13W-I
- TOXIC EFFECTS :
- Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 24 mg/kg/5D
- TOXIC EFFECTS :
- Blood - leukopenia
Blood - thrombocytopenia
Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Blood - changes in bone marrow (not otherwise specified)
Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human Leukocyte
- DOSE/DURATION :
- 2 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
36,3659,1976