氯胺酮
- 中文名称：
- 氯胺酮
- 中文别名：
- 氯胺酮;
凯他敏
- 英文名称：
- KETAMINE HYDROCHLORIDE SELECTIVE NMDA AN TAGO
- 英文别名：
- Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (.+-.)-;
KETAMINE HYDROCHLORIDE SELECTIVE NMDA AN TAGO;
Ketoject;
dl-Ketamine
- CAS No.：
- 6740-88-1
- 分 子 式：
-
C13H16ClNO
- 分 子 量：
- 237.72524
- 精确分子量：
- 237.09200
- PSA：
- 29.10000
- InChI：
- The Key: YQEZLKZALYSWHR-UHFFFAOYSA-N3
- 风险术语：
- 3249
- SDS：
- 查看
氯胺酮 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GW1300000
- CHEMICAL NAME :
- Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-,
(+-)-
- CAS REGISTRY NUMBER :
- 6740-88-1
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H16-Cl-N-O
- MOLECULAR WEIGHT :
- 237.75
- WISWESSER LINE NOTATION :
- L6VTJ BM1 BR BG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJANAD British Journal of Anesthesia. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1923- Volume(issue)/page/year:
55,457,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 77 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic
- REFERENCE :
- JZKEDZ Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental
Animals, Research Reports. (Jikken Dobutsu Chuo Kenkyusho, 1433 Nogawa,
Takatsu-ku, Kawasaki 211, Japan) V.1- 1975- Volume(issue)/page/year:
1,119,1975
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 1 mg/kg
- SEX/DURATION :
- female 23 week(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - other effects to embryo
- REFERENCE :
- BJANAD British Journal of Anesthesia. (Macmillan Press Ltd., Houndmills,
Basingstoke, Hants. RG21 2XS, UK) V.1- 1923- Volume(issue)/page/year:
47,917,1975
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X6267
No. of Facilities: 28 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 91 (estimated)
No. of Female Employees: 36 (estimated)