4-(4-氟苯基)乙酰苯胺,398-32-3，生产厂家，价格-洛克化工网移动版

4-(4-氟苯基)乙酰苯胺

中文名称：: 4-(4-氟苯基)乙酰苯胺

中文别名：: 4-(4-氟苯基)乙酰苯胺;
4'-(4-氟苯基)乙酰苯胺

英文名称：: Acetamide,N-(4'-fluoro[1,1'-biphenyl]-4-yl)-

英文别名：: N-[4-(4-fluorophenyl)phenyl]acetamide;
Acetamide,N-(4'-fluoro-4-biphenylyl);
4'-Fluor-4-biphenylacetanilid;
4'-Fluoro-4-acetylaminobiphenyl;
4'-(p-Fluorophenyl)acetanilide;
N-4-(4'-Fluoro)biphenylacetamide;
N-(4'-Fluoro-4-biphenylyl)acetamide;
ACETANILIDE,4'-(p-FLUOROPHENYL);
N-(4'-Fluor-biphenyl-4-yl)-acetamid;
N-[4'-fluoro(1,1'-biphenyl)-4-yl]acetamide;
4'-Fluor-4-acetamino-diphenyl;
4-Fluoro-4'-acetamidobiphenyl;
EINECS 206-912-7;
4-Acetamido-4'-fluorbiphenyl;
N-(4'-fluoro-biphenyl-4-yl)-acetamide;
4'-Fluoro-4-biphenylacetamide

CAS No.：: 398-32-3

分子式：: C₁₄H₁₂FNO

分子量：: 229.25

精确分子量：: 229.09000

PSA：: 29.10000

MDL：: MFCD00017955

EINECS：: 206-912-7

InChI：: The Key: JORMZLCKCZMVJM-UHFFFAOYSA-N3

安全术语：: S24/25

分子结构式：

SDS：: 查看

4-(4-氟苯基)乙酰苯胺物化性质

密度：: 1.193g/cm3
熔点：: 205-207ºC
沸点：: 416.1ºC at 760mmHg
闪点：: 205.5ºC
折射率：: 1.593
存储条件/存储方法：: 密封储存，储存于阴凉、干燥的库房。
稳定性相关：: 常温常压下稳定，避免与氧化剂接触。
其它信息：: 1.      性状：米色或棕色结晶状粉末
2.      密度（g/mL,25℃）：未确定
3.      相对蒸汽密度（g/mL,空气=1）：未确定
4.      熔点（ºC）：未确定
5.      沸点（ºC,常压）：未确定
6.      沸点（ºC,11.2515mmHg）：未确定
7.      折射率(n20/D)：未确定
8.      闪点（ºF）：未确定
9.      比旋光度（º）：未确定
10.   自燃点或引燃温度（ºC）：未确定
11.   蒸气压（mmHg,25ºC）：未确定
12.   饱和蒸气压（kPa,25ºC）：未确定
13.   燃烧热（KJ/mol）：未确定
14.   临界温度（ºC）：未确定
15.   临界压力（KPa）：未确定
16.   油水（辛醇/水）分配系数的对数值：未确定
17.   爆炸上限（%,V/V）：未确定
18.   爆炸下限（%,V/V）：未确定
19.   溶解性：未确定

4-(4-氟苯基)乙酰苯胺安全信息

海关代码：: 2924299090
安全说明：: S24/25
安全标志：: S24/25:防止皮肤和眼睛接触。

4-(4-氟苯基)乙酰苯胺毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE3750000

CHEMICAL NAME :: Acetanilide, 4'-(p-fluorophenyl)-

CAS REGISTRY NUMBER :: 398-32-3

BEILSTEIN REFERENCE NO. :: 2806508

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C14-H12-F-N-O

MOLECULAR WEIGHT :: 229.27

WISWESSER LINE NOTATION :: FR DR DMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4032 mg/kg/24W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: AJPAA4 American Journal of Pathology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1925- Volume(issue)/page/year: 100,317,1980

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8064 mg/kg/48W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 64,1537,1980

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6048 mg/kg/36W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,217,1976

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg/36W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,427,1975

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6048 mg/kg/36W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 23,464,1979

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5040 mg/kg/36W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,1223,1975

毒理学数据：

1、急性毒性：大鼠经口TDLo：4032mg/kg/24W-C；大鼠经口TD：8064mg/kg/48W-C；大鼠经口LD50：6048mg/kg/36W-C；大鼠经口TD：5mg/kg/36W-I；大鼠经口TD：6048mg/kg/36W-C；大鼠经口TD：5040mg/kg/36W-C；

4-(4-氟苯基)乙酰苯胺 MSDS

Name:	4 -(4-Fluorophenyl)-acetanilide Material Safety Data Sheet
Synonym:	4-Fluoro-4-acetylaminobiphenyl; N-(4'-Fluoro-4-biphenyl)acetamide; N-4-(4'-fluoro)Biphenylacetamide
CAS:	398-32-3

Section 1 - Chemical Product MSDS Name:4 -(4-Fluorophenyl)-acetanilide Material Safety Data Sheet
Synonym:4-Fluoro-4-acetylaminobiphenyl; N-(4'-Fluoro-4-biphenyl)acetamide; N-4-(4'-fluoro)Biphenylacetamide

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
398-32-3	4'-(4-fluorophenyl)-acetanilide	100.0	206-912-7

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Remove contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Antidote: None reported.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 398-32-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 205.00 - 207.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: N/A
Explosion Limits, upper: N/A
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C14H12FNO
Molecular Weight: 229.25

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, fluoride fumes.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 398-32-3: AE3750000 LD50/LC50:
Not available.
Carcinogenicity:
4'-(4-fluorophenyl)-acetanilide - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
Other No information available.

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 398-32-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 398-32-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 398-32-3 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

4-(4-氟苯基)乙酰苯胺海关数据

中国海关编码：2924299090

概述：: 2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素：: 品名, 成分含量, 用途, 包装
摘要/Summary：: 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4-(4-氟苯基)乙酰苯胺分子结构与计算化学数据

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:1

3.氢键受体数量:2

4.可旋转化学键数量:2

5.互变异构体数量:3

6.拓扑分子极性表面积29.1

7.重原子数量:17

8.表面电荷:0

9.复杂度:253

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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