二氧化硫,7446-09-5，生产厂家，价格-洛克化工网移动版

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二氧化硫

中文名称：: 二氧化硫

中文别名：: 二氧化硫;
亚硫酸酐(液);
二氧化硫(液);
Selenium dioxide;
Selenium oxide;
dimethyl (4-methoxybenzylidene)propanedioate;
Dimethyl (p-methoxybenzylidene)malonate;
Calcium solution 1000 ppm;
Calcium solution 10 000 ppm;
Calcium;
Zinc Powder;
Zinc metal foil;
Zinc metal;
zinc dust;
Poster Color Deep Blue;
锌片;
锌;
Gold shot (99.9999%);
Gold wire (99.9999%);
Gold shot (99.95%);
CoppershotNmm;
Copper powder;
Copper, small rods for elemental ana

英文名称：: Sulfur dioxide

英文别名：: sulfur dioxide;
SULPHUR DIOXIDE;
Sulfur dioxide;
Schwefeldioxyd;
SO2;
sulfurousoxide;
dioxidedesoufre;
sulfuroxide;
Schwefeldioxid;
SulfureDioxide

CAS No.：: 7446-09-5

分子式：: O₂S

分子量：: 64.06

精确分子量：: 63.96190

PSA：: 66.23000

MDL：: MFCD00011450

EINECS：: 231-195-2

BRN：: 3535237

InChI：: InChI=1/O2S/c1-3-23

危险品标志：: T

风险术语：: R23;R24;

安全术语：: S9;S26;S36/37/39;S45;

分子结构式：

SDS：: 查看

二氧化硫制备方法及用途

制备方法

1.用氨水吸收硫酸厂尾气,吸收液含亚硫酸铵和亚硫酸氢铵,用硫酸分解可放出高浓度SO2气体,经干燥、压缩、分离和冷却即成液体产品。也可用硫黄与纯氧在焚硫炉内燃烧,生成高浓度的SO2气体,经干燥、压缩和冷凝成液体SO2。精制方法:液态二氧化硫中的杂质含有微量SO3、水、不挥发物质及空气成分(O2、N2、CO2等)。一般可直接作合成反应的溶剂使用。精制时可将液态二氧化硫气化,通入浓硫酸中以除去SO3,通入装有五氧化二磷的玻璃管或在盛有五氧化二磷的容器中进行蒸馏以除去水分。 2.氨酸法用硫酸分解硫酸厂尾气吸收工序所得的亚硫酸铵亚硫酸氢铵母液,产生的约100%二氧化硫气体,经压缩法和冷冻法,可制得二氧化硫。 3.压缩法用硫酸分解亚硫酸铵亚硫酸氢铵母液,分解产生的二氧化硫气体,经冷凝、干燥、过滤,再经压缩液化,制得液体二氧化硫成品。其反应式如下。 4.冷冻法用硫酸分解亚硫酸铵亚硫酸氢铵母液,分解产生的二氧化硫气体经干燥后送至低温冷凝器,在常压下进行冷凝,用氨冷冻维持温度在液化点-10℃以下。制得液体二氧化硫成品。其反应式如下。 5.纯氧燃烧法将硫磺与纯氧在焚硫炉内燃烧,生成的高浓度二氧化硫气体,经净化、干燥、压缩液化、冷凝,制得二氧化硫成品。其反应式如下。 6.柠檬酸钠法经过净化的二氧化硫气体用柠檬酸钠溶液吸收,再用低压蒸汽脱出二氧化硫,经冷却、分离冷凝水,用浓硫酸进行干燥,然后经压缩液化、冷凝,制得液体二氧化硫成品。

合成制备方法

1.用氨水吸收硫酸厂尾气，吸收液含亚硫酸铵和亚硫酸氢铵,用硫酸分解可放出高浓度SO2气体，经干燥、压缩、分离和冷却即成液体产品。也可用硫黄与纯氧在焚硫炉内燃烧，生成高浓度的SO2气体，经干燥、压缩和冷凝成液体SO2。

精制方法：液态二氧化硫中的杂质含有微量SO3、水、不挥发物质及空气成分（O2、N2、CO2等）。一般可直接作合成反应的溶剂使用。精制时可将液态二氧化硫气化，通入浓硫酸中以除去SO3，通入装有五氧化二磷的玻璃管或在盛有五氧化二磷的容器中进行蒸馏以除去水分。

2.氨酸法　用硫酸分解硫酸厂尾气吸收工序所得的亚硫酸铵亚硫酸氢铵母液，产生的约100%二氧化硫气体，经压缩法和冷冻法，可制得二氧化硫。

3.压缩法用硫酸分解亚硫酸铵亚硫酸氢铵母液，分解产生的二氧化硫气体，经冷凝、干燥、过滤，再经压缩液化，制得液体二氧化硫成品。其反应式如下。

4.冷冻法用硫酸分解亚硫酸铵亚硫酸氢铵母液，分解产生的二氧化硫气体经干燥后送至低温冷凝器，在常压下进行冷凝，用氨冷冻维持温度在液化点－10℃以下。制得液体二氧化硫成品。其反应式如下。

5.纯氧燃烧法　将硫磺与纯氧在焚硫炉内燃烧，生成的高浓度二氧化硫气体，经净化、干燥、压缩液化、冷凝，制得二氧化硫成品。其反应式如下。

6.柠檬酸钠法　经过净化的二氧化硫气体用柠檬酸钠溶液吸收，再用低压蒸汽脱出二氧化硫，经冷却、分离冷凝水，用浓硫酸进行干燥，然后经压缩液化、冷凝，制得液体二氧化硫成品。

用途简介

1.二氧化硫是我国允许使用的还原性漂白剂。对食品有漂白和对植物性食品内的氧化酶有强烈的抑制作用。我国规定可用于葡萄酒和果酒,最大使用量0.25g/kg,残留量不得超过0.05g/kg。主要用于生产三氧化硫、硫酸、亚硫酸盐、硫代硫酸盐,也用作熏蒸剂、漂白剂、防腐剂、消毒剂、还原剂等。 2.主要用作硫酸的制造原料,也用作多种有机化学反应的溶剂。在液态二氧化硫中阳离子或阳碳离子与液态二氧化硫分子都能独立存在,而对阴离子的溶剂化作用强。因此液态二氧化硫作溶剂有利于阳离子作为反应中间体的化学反应,可加快反应速度。例如Beckmann重排反应,Wager Meerwein重排反应,酯化反应等。液态二氧化硫作溶剂也有利于阳离子聚合反应和顺反异构的异构化反应。此外液态二氧化硫还可用于熏蒸剂、杀虫剂、水果蔬菜防腐剂、杀菌剂、纤维漂白剂以及矿物油的精制、各种亚硫酸盐的制造、镁的冶炼等。 3.在工业中是多种化合物的良好溶剂。可用作冷冻剂、防腐剂、漂白剂及其他有机产品的原料。也用于制造保险粉和亚硫酸盐等。还用于农药、医药、人造纤维及染料等工业部门。 4.用于制造硫酸和保险粉等。

用途

1.二氧化硫是我国允许使用的还原性漂白剂。对食品有漂白和对植物性食品内的氧化酶有强烈的抑制作用。我国规定可用于葡萄酒和果酒，最大使用量0.25g/kg，残留量不得超过0.05g/kg。主要用于生产三氧化硫、硫酸、亚硫酸盐、硫代硫酸盐，也用作熏蒸剂、漂白剂、防腐剂、消毒剂、还原剂等。

2.主要用作硫酸的制造原料，也用作多种有机化学反应的溶剂。在液态二氧化硫中阳离子或阳碳离子与液态二氧化硫分子都能独立存在，而对阴离子的溶剂化作用强。因此液态二氧化硫作溶剂有利于阳离子作为反应中间体的化学反应，可加快反应速度。例如Beckmann重排反应，Wager Meerwein重排反应，酯化反应等。液态二氧化硫作溶剂也有利于阳离子聚合反应和顺反异构的异构化反应。此外液态二氧化硫还可用于熏蒸剂、杀虫剂、水果蔬菜防腐剂、杀菌剂、纤维漂白剂以及矿物油的精制、各种亚硫酸盐的制造、镁的冶炼等。

3.在工业中是多种化合物的良好溶剂。可用作冷冻剂、防腐剂、漂白剂及其他有机产品的原料。也用于制造保险粉和亚硫酸盐等。还用于农药、医药、人造纤维及染料等工业部门。

4.用于制造硫酸和保险粉等。^[23]

二氧化硫物化性质

外观与性状：: 白色至黄色固体
密度：: 1.25 g/mL at 25 °C(lit.)
熔点：: −73 °C(lit.)
沸点：: −10 °C(lit.)
折射率：: 1.3047 (20ºC)
蒸汽密度：: 2.26 (21 °C, vs air)
存储条件/存储方法：: 库房通风低温干燥,与氧化剂、易燃物分开存放
稳定性相关：: 1.在常温下，潮湿的二氧化硫与硫化氢起反应析出硫。在高温及催化剂存在的条件下，可被氢还原成为硫化氢，被一氧化碳还原成硫。强氧化剂可将二氧化硫氧化成三氧化硫，仅在催化剂存在时，氧才能使二氧化硫氧化为三氧化硫。具有自燃性，无助燃性。液态二氧化硫能溶解如胺、醚、醇、苯酚、有机酸、芳香烃等有机化合物，多数饱和烃不溶解。有一定的水溶性，与水及水蒸气作用生成有毒及腐蚀性蒸气。无机化合物如溴、三氯化硼、二硫化碳、三氯化磷、磷酰氯、氯化碘以及各种亚硫酰氯化物都可以任何比例与液态二氧化硫混合。碱金属卤化物在液态二氧化硫中的溶解度按I->Br->Cl-的次序减小。金属氧化物、硫化物、硫酸盐等多数不溶于液态二氧化硫。
2.化学性质：液态二氧化硫比较稳定，不活泼。气态二氧化硫加热到2000℃不分解。不燃烧，与空气也不组成爆炸性混合物。化学性质极其复杂，不同的温度可表现出非质子溶剂、路易氏酸、还原剂、氧化剂、氧化还原试剂等各种作用。液态二氧化硫还可作自由基接受体。如在偶氮二异丁腈自由基引发剂存在下与乙烯化合物反应得到聚砜。液态二氧化硫在光照下，可与氯和烷烃进行氯磺化反应，在氧存在下生成磺酸。液态二氧化硫在低温表现出还原作用，但在300℃以上表现出氧化作用。
3.稳定性^[18] 稳定
4.禁配物^[19] 强还原剂、强氧化剂、易燃或可燃物
5.避免接触的条件^[20] 潮湿空气
6.聚合危害^[21] 不聚合
其它信息：: 1.性状：无色气体，有刺激性气味。^[1]
2.熔点（℃）：-75.5^[2]
3.沸点（℃）：-10^[3]
4.相对密度（水=1）：1.4（-10℃）^[4]
5.相对蒸气密度（空气=1）：2.25^[5]
6.饱和蒸气压（kPa）：330（20℃）^[6]
7.临界温度（℃）：157.8^[7]
8.临界压力（MPa）：7.87^[8]
9.辛醇/水分配系数：-2.20^[9]
10.溶解性：溶于水、乙醇、乙醚。^[10]
11.黏度（mPa·s,0ºC）：0.3936
12.黏度（mPa·s,-10.5ºC）：0.4285
13.黏度（mPa·s,-15ºC）：0.4521
14.黏度（mPa·s,-33.5ºC）：0.5508
15.蒸气压（kPa,-268C）：338.42
16.蒸气压（mmHg,21ºC）：1779
17.蒸发热（KJ/mol,-10.08ºC）：24.95
18.熔化热（KJ/mol）：7.41
19.生成热（KJ/mol,25ºC）：297.01
20.沸点上升常数：1.48
21.电导率（S/m）：3×10^-8

二氧化硫毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WS4550000

CHEMICAL NAME :: Sulfur dioxide

CAS REGISTRY NUMBER :: 7446-09-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 87

MOLECULAR FORMULA :: O2-S

MOLECULAR WEIGHT :: 64.06

WISWESSER LINE NOTATION :: S O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 1000 ppm/10M

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 3 ppm/5D

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 12 ppm/1H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 3000 ppm/5M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2520 ppm/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3000 ppm/30M

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1039 ppm/24H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 1 pph/15M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3000 ppm/5M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4910 ug/m3/6H/17W-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - cytochrome oxidases (including oxidative phosphorylation) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ug/m3/96D-I

TOXIC EFFECTS :: Brain and Coverings - changes in surface EEG Behavioral - changes in motor activity (specific assay) Biochemical - Metabolism (Intermediary) - xanthine, purine or nucleotides including urate

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 ppm/3H/6W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 ppm/24H/14D-I

TOXIC EFFECTS :: Behavioral - food intake (animal) Liver - other changes Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1 ppm/90M/1Y-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 500 ppm/2H/21W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - respiratory depression

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/m3/3H/13W-I

TOXIC EFFECTS :: Cardiac - other changes Liver - other changes Blood - hemorrhage

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 10 ppm/1H/30D-I

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 ppm/5M/30W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 4 mg/m3/24H

SEX/DURATION :: female 72 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Maternal Effects - parturition Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 4 mg/m3/24H

SEX/DURATION :: female 72 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - delayed effects

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 4970 ug/m3/12H

SEX/DURATION :: female 12 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 30 ppm/6H

SEX/DURATION :: male 21 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 25 ppm/7H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 25 ppm/7H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 32 ppm/24H

SEX/DURATION :: female 7-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 70 ppm/7H

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Mammal - cattle Cells - not otherwise specified

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,149,1977 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-STEL 13 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 5.2 mg/m3 (2 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,131,1992 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,131,1992 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 54,131,1992 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 11,163,1975 TOXICOLOGY REVIEW NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB228-002 TOXICOLOGY REVIEW EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 10,35,1975 TOXICOLOGY REVIEW GEIGAI Gendai Igaku. Current Medicine. (Aichi-ken Ishikai, 14-28, Sakae 4-chome, Naka-ku, Nagoya 460, Japan) V.1- 1950- Volume(issue)/page/year: 20,299,1973 TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 16,903,1968 TOXICOLOGY REVIEW ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 16,139,1978 TOXICOLOGY REVIEW NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: CONF-691001 TOXICOLOGY REVIEW AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,455,1954 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 5 ppm (13 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,238,1971 OSHA PEL (Gen Indu):8H TWA 5 ppm (13 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 5 ppm (13 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 5 ppm (13 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 5 ppm (13 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 5 ppm (13 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 2 ppm (5 mg/m3);STEL 5 ppm (10 mg/m3) JAN 1993 OEL-BELGIUM:TWA 2 ppm (5.2 mg/m3);STEL 5 ppm (13 mg/m3) JAN 1993 OEL-DENMARK:TWA 2 ppm (5 mg/m3) JAN 1993 OEL-FINLAND:TWA 2 ppm (5 mg/m3);STEL 5 ppm (13 mg/m3) JAN 1993 OEL-FRANCE:TWA 2 ppm (5 mg/m3);STEL 5 ppm (10 mg/m3) JAN 1993 OEL-GERMANY:TWA 2 ppm (5 mg/m3) JAN 1993 OEL-HUNGARY:TWA 3 mg/m3;STEL 6 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 2 ppm (5 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 5 ppm (13 mg/m3) JAN 1993 OEL-POLAND:TWA 20 mg/m3 JAN 1993 OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 2 ppm (5 mg/m3);STEL 5 ppm (13 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 2 ppm (5 mg/m3);STEL 4 ppm (10 mg/m3) JAN 1993 OEL-THAILAND:TWA 5 ppm (13 mg/m3) JAN 1993 OEL-TURKEY:TWA 5 ppm (13 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 2 ppm (5 mg/m3);STEL 5 ppm (13 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO SULFUR DIOXIDE-air:10H TWA 2 ppm;STEL 5 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 70860 No. of Facilities: 6399 (estimated) No. of Industries: 85 No. of Occupations: 61 No. of Employees: 51398 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 70860 No. of Facilities: 2465 (estimated) No. of Industries: 59 No. of Occupations: 58 No. of Employees: 55033 (estimated) No. of Female Employees: 8990 (estimated)

毒理学数据：

1、大鼠吸入（1h）LC50：6600mg/m3。ADI 0～70mg/kg(以SO2计，包括SO2和亚硫酸盐的总ADI；FAO/WHO，2001)。对眼及呼吸道黏膜有强烈的刺激作用。SO2在空气中浓度达0.04％～0.05％时，人就会中毒。

2、属中等毒类，易被湿润的黏膜表面吸收而生成亚硫酸，其中部分氧化为硫酸，故对呼吸道和眼有强烈的刺激作用。轻度中毒时发生流泪、畏光、咳嗽、鼻、咽、喉部灼烧样痛、声音嘶哑，甚至呼吸短促、胸闷、胸痛。有时还会出现恶心、呕吐、上腹痛、头痛、头昏、全身无力等症状。严重中毒时于数小时内发生肺水肿、呼吸困难、紫绀、支气管痉挛而引起急性肺气肿。空气中的浓度为7.86~13.1mg/m3时人可感觉到，52.4mg/m3时刺激眼黏膜，1048~1310mg/m3时短时间即有生命危险。最高容许浓度为20mg/m3。

3.急性毒性^[11] LC50：6600mg/m³；2520ppm（大鼠吸入，1h）

4.刺激性^[12] 家兔经眼：6ppm（4h），共32d，轻度刺激。

5.亚急性与慢性毒性^[13] 小鼠吸入本品5.24mg/m³，半年，出现免疫反应受抑制。

6.致突变性^[14] DNA损伤：人淋巴细胞5700ppb。DNA抑制：人淋巴细胞5700ppb。细胞遗传学分析和姐妹染色单体交换：人多种接触途径42mg/m³。

7.致畸性^[15] 兔孕后6~18d吸入最低中毒剂量（TCLo）70ppm（7h），致肌肉骨骼系统发育畸形。

8.其他^[16] 大鼠吸入最低中毒浓度（TCLo）：4mg/m³，（24h）（交配前72d），引起发情周期改变或失调，对分娩有影响，对雌性生育指数有影响。小鼠吸入最低中毒浓度（TCLo）：25ppm（7h）（孕6~15d），引起胚胎毒性。

人吸入LCLo：1000ppm（10min）；TCLo：3ppm（5d）；400~500ppm，立即危及生命。

生态数据：

1.生态毒性 暂无资料

2.生物降解性 暂无资料

3.非生物降解性 暂无资料

4.其他有害作用^[17] 该物质可严重污染大气，由其形成的酸与对植物的危害尤为严重。

二氧化硫

二氧化硫制备方法及用途

制备方法

合成制备方法

用途简介

用途

二氧化硫物化性质

二氧化硫安全信息

二氧化硫毒理性

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

二氧化硫 MSDS

二氧化硫分子结构与计算化学数据

分子结构数据

计算化学数据

二氧化硫下游产品

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二氧化硫

二氧化硫 制备方法及用途

制备方法

合成制备方法

用途简介

用途

二氧化硫 物化性质

二氧化硫 安全信息

二氧化硫 毒理性

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

二氧化硫 MSDS

二氧化硫 分子结构与计算化学数据

分子结构数据

计算化学数据

二氧化硫 下游产品

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二氧化硫制备方法及用途

二氧化硫物化性质

二氧化硫安全信息

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二氧化硫分子结构与计算化学数据

二氧化硫下游产品