4-溴甲基-7-乙酸香豆素,2747-04-8，生产厂家，价格-洛克化工网移动版

4-溴甲基-7-乙酸香豆素

中文名称：: 4-溴甲基-7-乙酸香豆素

中文别名：: 7-乙酰氧基-4-溴甲基香豆素;
4-溴甲基-7-乙酸香豆素

英文名称：: 2H-1-Benzopyran-2-one,7-(acetyloxy)-4-(bromomethyl)-

英文别名：: [4-(bromomethyl)-2-oxochromen-7-yl] acetate;
7-ACETOXY-4-BROMOMETHYLCOUMARIN;
BR-MAC;
7-Acetoxy-4-brommethyl-cumarin;
7-acetoxy-4-bromomethyl-2H-1-benzopyran-2-one;
4-Bromomethyl-7-acetoxycoumarin;
7-acetoxy-4-bromomethyl-coumarin;
7-acetoxy-4-bromomethyl-chromen-2-one

CAS No.：: 2747-04-8

分子式：: C₁₂H₉BrO₄

分子量：: 297.1

精确分子量：: 295.96800

PSA：: 56.51000

InChI：: The Key: YDJFMNSSDOXBSR-UHFFFAOYSA-N3

风险术语：: R34

安全术语：: S22 S26 S27 S45 S36/S37/S39

分子结构式：

SDS：: 查看

4-溴甲基-7-乙酸香豆素物化性质

密度：: 1.589g/cm3
熔点：: 180-182°C
沸点：: 414.4ºC at 760mmHg
闪点：: 204.4ºC
折射率：: 1.594
蒸汽压：: 4.46E-07mmHg at 25°C
存储条件/存储方法：: 密闭于阴凉干燥环境中
稳定性相关：: 遵照规定使用和储存则不会分解。
其它信息：: 1.       性状：无可用

2.       密度（g/mL,25/4℃）：无可用

3.       相对蒸汽密度（g/mL,空气=1）：无可用

4.       熔点（ºC）：180-182

5.       沸点（ºC,常压）：无可用

6.       沸点（ºC,5.2kPa）：无可用

7.       折射率：无可用

8.       闪点（ºC）：无可用

9.       比旋光度（º）：无可用

10.    自燃点或引燃温度（ºC）：无可用

11.    蒸气压（kPa,25ºC）：无可用

12.    饱和蒸气压（kPa,60ºC）：无可用

13.    燃烧热（KJ/mol）：无可用

14.    临界温度（ºC）：无可用

15.    临界压力（KPa）：无可用

16.    油水（辛醇/水）分配系数的对数值：无可用

17.    爆炸上限（%,V/V）：无可用

18.    爆炸下限（%,V/V）：无可用

19.    溶解性：无可用

4-溴甲基-7-乙酸香豆素安全信息

包装等级：: III
风险类别：: 8
海关代码：: 2932209090
危险类别码：: 34
安全说明：: S22-S26-S36/37/39-S45-S27
安全标志：: S22:不要吸入粉尘。
S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S27:立刻除去所有污染衣物。
S45:出现意外或者感到不适，立刻到医生那里寻求帮助（最好带去产品容器标签）。
:
危险标志：: C: Corrosive;

4-溴甲基-7-乙酸香豆素毒理性

生态数据：

该物质对环境可能有危害，对水体应给予特别注意。

4-溴甲基-7-乙酸香豆素 MSDS

7-Acetoxy-4-bromomethylcoumarin [for HPLC Labeling] Revision number: 1
SAFETY DATA SHEET

Section 1. BASE INFORMATION
Product name: 7-Acetoxy-4-bromomethylcoumarin [for HPLC Labeling]

Revision number: 1

Section 2. HAZARDS IDENTIFICATION
  Classification of the GHS
  PHYSICAL HAZARDS
  Corrosive to metals        Category 1
  HEALTH HAZARDS
  Skin corrosion/irritation        Category 1B
    Category 1
  Serious eye damage/eye irritation
  ENVIRONMENTAL HAZARDS        Not classified
  GHS label elements
  Pictograms or hazard symbols
  Signal word        Danger
  Hazard statement        May be corrosive to metals
    Causes severe skin burns and eye damage
  Precautionary statements
    Keep only in original container.
  [Prevention]
    Do not breathe.
    Wash hands thoroughly after handling.
    Wear protective gloves/eye protection/face protection.
    IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for
  [Response]
    breathing.
    IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
    if present and easy to do. Continue rinsing.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse
    skin with water/shower.
    Wash contaminated clothing before reuse.
    Immediately call a POISON CENTER or doctor/physician.
    Absorb spillage to prevent material damage.
  [Storage]        Store locked up.
  [Disposal]        Dispose of contents/container through a waste management company authorized by
    the local government

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
    Substance
  Substance/mixture:
  Labeling]

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Component(s):        7-Acetoxy-4-bromomethylcoumarin [for HPLC Labeling]
  Percent:        >98.0%(LC)(T)
  CAS Number:        2747-04-8
  Chemical Formula:        C12H9BrO4

Section 4. FIRST AID MEASURES
    Remove victim to fresh air and keep at rest in a position comfortable for breathing.
  Inhalation:
    Immediately call a POISON CENTER or doctor/physician.
  Skin contact:        Remove/Take off immediately all contaminated clothing. Gently wash with plenty of
    soap and water. Immediately call a POISON CENTER or doctor/physician.
  Eye contact:        Rinse cautiously with water for several minutes. Remove contact lenses, if present
    and easy to do. Continue rinsing.Immediately call a POISON CENTER or
    doctor/physician.
  Ingestion:        Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT
    induce vomiting.
    A rescuer should wear personal protective equipment, such as rubber gloves and air-
  Protection of first-aiders:
    tight goggles.

Section 5. FIRE-FIGHTING MEASURES
  Suitable extinguishing        Dry chemical, foam, water spray, carbon dioxide.
  media:
  Specific hazards:        Take care as it may decompose upon combustion or in high temperatures to
    generate poisonous fume.
  Specific methods:        Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
    method according to the surrounding situation is used. Uninvolved persons should
    evacuate to a safe place. In case of fire in the surroundings: Remove movable
    containers if safe to do so.
  Special protective        When extinguishing fire, be sure to wear personal protective equipment.
  equipment for firefighters:

Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions,        Use extra personal protective equipment (P3 filter respirator for toxic particles). Keep
  protective equipment and people away from and upwind of spill/leak. Entry to non-involved personnel should
  emergency procedures: be controlled around the leakage area by roping off, etc.
  Environmental precautions: Prevent product from entering drains.
  Methods and materials for Sweep dust to collect it into an airtight container, taking care not to disperse it.
  containment and cleaning Adhered or collected material should be promptly disposed of, in accordance with
  up: appropriate laws and regulations.

Section 7. HANDLING AND STORAGE
  Handling
  Technical measures:        Handling is performed in a well ventilated place. Wear suitable protective equipment.
    Prevent dispersion of dust. Wash hands and face thoroughly after handling.
    Use a closed system if possible. Use a local exhaust if dust or aerosol will be
    generated.
  Advice on safe handling:        Avoid contact with skin, eyes and clothing.
    Use corrosive resistant equipment.
  Storage
  Storage conditions:        Keep container tightly closed. Store in a cool and dark place.
    Store under inert gas.
    Protect from moisture.
    Store locked up.
    Store away from incompatible materials such as oxidizing agents.
  Packaging material:        Law is followed. Keep only in original container.
  Labeling]

Section 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
  Engineering controls:        Install a closed system or local exhaust. Also install safety shower and eye bath.
  Personal protective equipment
  Respiratory protection: Dust respirator, self-contained breathing apparatus(SCBA), supplied air respirator,
    etc. Use respirators approved under appropriate government standards and follow
    local and national regulations.
    Impervious gloves.
  Hand protection:
  Eye protection:        Safety goggles. A face-shield, if the situation requires.
  Skin and body protection: Impervious protective clothing. Protective boots, if the situation requires.

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Physical state (20°C):        Solid
  Form:        crystal - powder
    White - Slightly pale yellow
  Color:
  Odor:        No data available
  pH: No data available
  Melting point/freezing point:182 °C
  Boiling Point/Range:        No data available
  Flash Point:        No data available
  Explosive limits
  Lower:        No data available
    No data available
  Upper:
  Density:        No data available
    No data available
  Solubility:

Section 10. STABILITY AND REACTIVITY
  Stability:        Stable under proper conditions.
  Reactivity:        No special reactivity has been reported.
  Conditions to avoid:        Light-sensitive, Moisture-sensitive
  Incompartible materials: oxidizing agents, bases
  Hazardous Decomposition Carbon monoxide, Carbon dioxide, Hydrogen bromide
  Products:

Section 11. TOXICOLOGICAL INFORMATION
    No data available
  Acute Toxicity:
  Skin corrosion/irritation: No data available
  Serious eye        No data available
  damage/irritation:
  Germ cell mutagenicity: No data available
  Carcinogenicity:
    No data available
  IARC =
  NTP =        No data available
    No data available
  Reproductive toxicity:

Section 12. ECOLOGICAL INFORMATION
  Ecotoxicity:
  Fish:        No data available
  Crustacea:        No data available
  Algae:        No data available
  Persistence / degradability: No data available
  Bioaccumulative        No data available
  potential(BCF):
  Mobillity in soil
  log Pow:        No data available
  Soil adsorption (Koc):        No data available
  Henry's Law        No data available
  constant(PaM3/mol):
  Labeling]

Section 13. DISPOSAL CONSIDERATIONS
    Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
    Observe all federal, state and local regulations when disposing of the substance.

Section 14. TRANSPORT INFORMATION
    8: Corrosive.
  Hazards Class:
  UN-No:        3261
    Corrosive solid, acidic, organic, n.o.s.
  Proper shipping name:
  Packing group:        II

Section 15. REGULATORY INFORMATION
  Safe management ordinance of dangerous chemical product (State Council announces on January 26,
  2002): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were
    prescribed.

SECTION 16 - ADDITIONAL INFORMATION
N/A

4-溴甲基-7-乙酸香豆素海关数据

中国海关编码：2932209090

概述：: 2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素：: 品名, 成分含量, 用途
摘要/Summary：: 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-溴甲基-7-乙酸香豆素分子结构与计算化学数据

分子结构数据

1、摩尔折射率：63.52

2、摩尔体积（m³/mol）：186.9

3、等张比容（90.2K）：498.6

4、表面张力（dyne/cm）：50.6

5、极化率（10^-24cm³）：25.18

计算化学数据

1、疏水参数计算参考值（XlogP）：2.2

2、氢键供体数量：0

3、氢键受体数量：4

4、可旋转化学键数量：3

5、拓扑分子极性表面积（TPSA）：52.6

6、重原子数量：17

7、表面电荷：0

8、复杂度：364

9、同位素原子数量：0

10、确定原子立构中心数量：0

11、不确定原子立构中心数量：0

12、确定化学键立构中心数量：0

13、不确定化学键立构中心数量：0

14、共价键单元数量：1

4-溴甲基-7-乙酸香豆素上游产品

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