4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE
- 中文名称：
- 4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE
- 中文别名：
- 4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE
- 英文名称：
- 4-amino-5-chloro-2-methoxy-N-piperidin-4-ylbenzamide
- 英文别名：
- 4-amino-5-chloro-2-methoxy-N-piperidin-4-ylbenzamide;
4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE;
4-amino-5-chloro-2-methoxy-N-4-piperidinyl-benzamide;
4-(4-amino-5-chloro-2-methoxy-benzoylamino)-piperidine-1-carboxylic acid;
Desbenzylclebopride;
N-<4'-Piperidyl>-2-methoxy-4-amino-5-chlorbenzamid;
BENZAMIDE,4-AMINO-5-CHLORO-2-METHOXY-N-(4-PIPERIDYL);
4-Amino-5-chloro-2-methoxy-N-(4-piperidyl)benzamide;
N-(piperid-4-yl)-2-methoxy-4-amino-5-chlorobenzamide
- CAS No.：
- 57645-49-5
- 分 子 式：
-
C13H18ClN3O2
- 分 子 量：
- 283.75400
- 精确分子量：
- 283.10900
- PSA：
- 76.38000
- InChI：
- The Key: RUQHFNWNPDBISK-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE 物化性质
- 密度：
- 1.29g/cm3
- 沸点：
- 440.9ºC at 760 mmHg
- 闪点：
- 220.5ºC
- 折射率：
- 1.596
4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU9395000
- CHEMICAL NAME :
- Benzamide,
4-amino-5-chloro-2-methoxy-N-(4-piperidyl)-
- CAS REGISTRY NUMBER :
- 57645-49-5
- BEILSTEIN REFERENCE NO. :
- 0482803
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C13-H18-Cl-N3-O2
- MOLECULAR WEIGHT :
- 283.79
- WISWESSER LINE NOTATION :
- T6MTJ DMVR DZ CG FO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2550 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay)
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 25,865,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 25,865,1983
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8750 mg/kg/5W-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal)
Endocrine - other changes
Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 25,865,1983
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3500 mg/kg
- SEX/DURATION :
- female 35 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 25,865,1983
4-AMINO-5-CHLORO-2-METHOXY-N-PIPERIDIN-4-YL-BENZAMIDE 上游产品
