溴甲烷,74-83-9，生产厂家，价格-洛克化工网移动版

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基本信息

制备方法及用途

物化性质

安全信息

毒理性

MSDS

海关数据

结构与计算化学

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溴甲烷

中文名称：: 溴甲烷

中文别名：: 溴甲烷;
甲基溴

英文名称：: Methyl bromide

英文别名：: bromomethane;
Bercema;
methyl bromide;
Terabol;
Methylbromid;
Pestmaster;
METHYL BROMIDE;
Methane,bromo;
Embafume

CAS No.：: 74-83-9

分子式：: CH₃Br

分子量：: 94.94

精确分子量：: 93.94180

PSA：: 0.00000

MDL：: MFCD00000166

EINECS：: 200-813-2

InChI：: InChI=1/CH3Br/c1-2/h1H33

危险品标志：

风险术语：: R23/25;R36/37/38;R48/20;R50;R59;R68;

安全术语：: S15;S27;S36/39;S38;S45;S59;S61;

分子结构式：

SDS：: 查看

溴甲烷物化性质

外观与性状：
无色气体带有一种像氯仿一样的气味

密度：
3.3 g/mL at 25 °C(lit.)

熔点：
−94 °C(lit.)

沸点：
4 °C(lit.)

闪点：
-34 °C

水溶解性：
1.522 g/100 mL

折射率：
1.4432

蒸汽密度：
3.3 (20 °C, vs air)

存储条件/存储方法：
库房通风低温干燥,轻装轻卸,与助燃气体分开存放

稳定性相关：

1.稳定性^[26] 稳定
2.禁配物^[27] 强氧化剂、碱金属或活性金属粉末（如镁、铝等）、二甲亚砜等
3.聚合危害^[28] 不聚合
4.分解产物^[29] 溴化氢

其它信息：

1.性状：无色气体，有甜味。^[1]
2.熔点（℃）：-93.6^[2]
3.沸点（℃）：3.6^[3]
4.相对密度（水=1）：1.73^[4]
5.相对蒸气密度（空气=1）：3.3^[5]
6.饱和蒸气压（kPa）：215.5（25℃）^[6]
7.燃烧热（kJ/mol）：-787.0^[7]
8.临界温度（℃）：194^[8]
9.临界压力（MPa）：8.45^[9]
10.辛醇/水分配系数：1.19^[10]
11.闪点（℃）：-44^[11]
12.引燃温度（℃）：537^[12]
13.爆炸上限（%）：16.0^[13]
14.爆炸下限（%）：10.0^[14]
15.溶解性：不溶于水，溶于乙醇、乙醚、氯仿、苯等多数有机溶剂。^[15]
16.熔化热（KJ/mol,179.48K）：5.98
17.生成热（KJ/mol,25ºC,气体）：34.3
18.比热容（KJ/(kg·K),-13ºC）：0.825
19.比热容（KJ/(kg·K),25ºC,定压）：0.448
20.电导率（S/m,0ºC）：122×10^-10
21.溶解度（%,水,20ºC）：1.75
22.热导率（W/(m·K),20ºC）：7.1176×10^-3
23.体膨胀系数（K^-1,-15~3ºC）：0.00163
24.Lennard-Jones参数（A）：8.153
25.Lennard-Jones参数（K）：162.2
26.溶度参数(J·cm^-3)^0.5：19.951
27.van der Waals面积（cm²·mol^-1）：4.200×10⁹
28.van der Waals体积（cm³·mol^-1）：28.070

溴甲烷安全信息

风险类别：
2.3

海关代码：
2903399020

WGK_Germany：
3
德国有关水污染物质的分类清单

危险类别码：
R23/25;R36/37/38;R48/20;R50;R59;R68

安全说明：
S15-S27-S36/39-S38-S45-S59-S61-S36/37-S26-S24-S16-S7

RTECS号：
PA4900000

危险标志：
T:Toxic

溴甲烷毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PA4900000

CHEMICAL NAME :
Methane, bromo-

CAS REGISTRY NUMBER :
74-83-9

LAST UPDATED :
199801

DATA ITEMS CITED :
78

MOLECULAR FORMULA :
C-H3-Br

MOLECULAR WEIGHT :
94.95

WISWESSER LINE NOTATION :
E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA

TYPE OF TEST :
LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Human - man

DOSE/DURATION :
60000 ppm/2H

TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Gastrointestinal - nausea or vomiting

TYPE OF TEST :
LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Human - child

DOSE/DURATION :
1 gm/m3/2H

TOXIC EFFECTS :
Blood - change in clotting factors

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Human

DOSE/DURATION :
35 ppm

TOXIC EFFECTS :
Behavioral - anorexia (human) Gastrointestinal - nausea or vomiting Skin and Appendages - corrosive (after topical exposure)

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Administration onto the skin

SPECIES OBSERVED :
Human

DOSE/DURATION :
35 gm/m3/40M-I

TOXIC EFFECTS :
Skin and Appendages - dermatitis, irritative (after systemic exposure)

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
214 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
302 ppm/8H

TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Nutritional and Gross Metabolic - weight loss or decreased weight gain Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
135 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
1540 mg/m3/2H

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Mammal - dog

DOSE/DURATION :
500 mg/kg

TOXIC EFFECTS :
Cardiac - pulse rate increase, without fall in BP Gastrointestinal - nausea or vomiting Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rabbit

DOSE/DURATION :
28900 mg/m3/30M

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - guinea pig

DOSE/DURATION :
300 ppm/9H

TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Skin and Appendages - hair

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
21840 mg/kg/2Y-C

TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Skin and Appendages - hair Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
120 ppm/6H/13W-I

TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
150 ppm/6H/5D-I

TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
160 ppm/6H/6W-I

TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Cardiac - other changes

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
300 ppm/4H/3W-I

TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Related to Chronic Data - death

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
200 ppm/6H/14D-I

TOXIC EFFECTS :
Related to Chronic Data - death

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
120 ppm/6H/13W-I

TOXIC EFFECTS :
Behavioral - muscle contraction or spasticity Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
160 ppm/6H/6W-I

TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Endocrine - other changes Blood - changes in spleen

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Primate - monkey

DOSE/DURATION :
250 mg/m3/8H/26W-I

TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - rabbit

DOSE/DURATION :
130 mg/m3/8H/26W-I

TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Related to Chronic Data - death

TYPE OF TEST :
TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :
Inhalation

SPECIES OBSERVED :
Rodent - guinea pig

DOSE/DURATION :
850 mg/m3/8H/26W-I

TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :
TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - rat

DOSE/DURATION :
3250 mg/kg/13W-I

TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - peritonitis Gastrointestinal - tumors

TYPE OF TEST :
Specific locus test

TYPE OF TEST :
Sex chromosome loss and nondisjunction

TYPE OF TEST :
Micronucleus test

TYPE OF TEST :
Micronucleus test

TYPE OF TEST :
Sister chromatid exchange
MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells

TEST SYSTEM :
Rodent - mouse Lymphocyte

REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 155,41,1985 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 3.9 mg/m3 (1 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,187,1986 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,187,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,245,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD-air:TWA 15 ppm (60 mg/m3) (skin) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,23,1973 OSHA PEL (Gen Indu):CL 20 ppm (80 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 20 ppm (80 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 20 ppm (80 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 20 ppm (80 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 5 ppm (20 mg/m3);Skin JAN 1993 OEL-AUSTRALIA:TWA 5 ppm (20 mg/m3);Skin JAN 1993 OEL-AUSTRIA:TWA 5 ppm (20 mg/m3) JAN 1993 OEL-BELGIUM:TWA 5 ppm (19 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 5 ppm (20 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 15 ppm (60 mg/m3);STEL 25 ppm (97 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (20 mg/m3) JAN 1993 OEL-GERMANY:TWA 5 ppm (20 mg/m3);Skin;Carcinogen JAN 1993 OEL-HUNGARY:TWA 10 mg/m3;STEL 20 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (20 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 20 ppm (80 mg/m3);Skin JAN 1993 OEL-POLAND:TWA 5 mg/m3 JAN 1993 OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 OEL-SWEDEN:TWA 15 ppm (60 mg/m3);STEL 20 ppm (80 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (20 mg/m3);STEL 10 ppm (40 mg/m3);Skin JAN 1993 OEL-THAILAND:TWA 20 ppm (80 mg/m3) JAN 1993 OEL-TURKEY:TWA 20 ppm (80 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (20 mg/m3);STEL 15 ppm;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHYL BROMIDE-air:CA lowest feasible concentration REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0420 No. of Facilities: 597 (estimated) No. of Industries: 10 No. of Occupations: 14 No. of Employees: 15899 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0420 No. of Facilities: 513 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 5603 (estimated) No. of Female Employees: 975 (estimated)

毒理学数据：

1.急性毒性^[16]
LD50：214mg/kg（大鼠经口）
LC50：302ppm（大鼠吸入，8h）；1540mg/m³（小鼠吸入，2h）
2.刺激性 暂无资料
3.亚急性与慢性毒性^[17] 吸入389mg/m³，98次，大鼠肺部从正常到严重肺炎，猴严重抽搐，豚鼠肺部无变化。
4.致突变性^[18] 微生物致突变：鼠伤寒沙门菌400ppm。姐妹染色单体交换：人淋巴细胞5mg/L。微核试验：大鼠吸入338ppm，每天6h，共14d。细胞遗传学分析：人淋巴细胞95mg/L。
5.致癌性^[19] IARC致癌性评论：G3，对人及动物致癌性证据不足。
6.其他^[20] TDLo：35000mg/m³（人经皮肤，40min）；LCLo：60000ppm（人吸入，2h）；TCLo：35ppm（人吸入）

生态数据：

1.生态毒性^[21] LC50：11~12mg/L（96h）（鱼类）
2.生物降解性^[22]
好氧生物降解（h）：168~672
厌氧生物降解（h）：672~2688
3.非生物降解性^[23]
空气中光氧化半衰期（h）：1633~16327
一级水解半衰期（h）：912
4.生物富集性^[24] BCF：270（理论）
5.其他有害作用^[25] 该物质对环境有危害，臭氧消耗物质，会对大气臭氧层造成破坏。

溴甲烷 MSDS

第一部分：化学品名称

溴甲烷海关数据

中国海关编码：2903399020

概述：

2903399020 溴甲烷〔别名甲基溴〕。监管条件:14abxy。增值税率:17.0%。退税率:0.0%。最低关税:5.5%。普通关税:30.0%

申报要素：

品名, 成分含量, 用途

监管条件：

1.进口许可证4.出口许可证A.入境货物通关单B.出境货物通关单x.出口许可证(加工贸易)y.出口许可证(边境小额贸易)

检验检疫：

M.进口商品检验N.出口商品检验

摘要/Summary：

2903399020 bromomethane。supervision conditions:14abxy。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:5.5%。general tariff:30.0%

溴甲烷分子结构与计算化学数据

分子结构数据

1、摩尔折射率：14.41
2、摩尔体积（cm³/mol）：58.2
3、等张比容（90.2K）：124.0
4、表面张力（dyne/cm）：20.6
5、介电常数：
6、偶极距（10-24cm3）：
7、极化率：5.71

计算化学数据

1.疏水参数计算参考值（XlogP）:1
2.氢键供体数量:0
3.氢键受体数量:0
4.可旋转化学键数量:0
5.互变异构体数量:无
6.拓扑分子极性表面积0
7.重原子数量:2
8.表面电荷:0
9.复杂度:2
10.同位素原子数量:0
11.确定原子立构中心数量:0
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:1

溴甲烷上游产品

磷酸三甲酯间二甲苯偏三甲苯邻二甲苯

溴甲烷下游产品

4-(3-羟基-丙基)-1-甲基-吡啶正离子, 溴化十四甲基环七硅氧烷六甲基环三硅氮烷八甲基环四硅氧烷十甲基环五硅氧烷

溴甲烷表征图谱

溴甲烷核磁图(¹HNMR)

溴甲烷质谱(MS)

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溴甲烷

溴甲烷制备方法及用途

制备方法

合成制备方法

用途简介

用途

溴甲烷物化性质

溴甲烷安全信息

溴甲烷毒理性

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

溴甲烷 MSDS

溴甲烷海关数据

中国海关编码：2903399020

溴甲烷分子结构与计算化学数据

分子结构数据

计算化学数据

溴甲烷上游产品

溴甲烷下游产品

溴甲烷表征图谱

推荐供应商

溴甲烷

溴甲烷 制备方法及用途