乙烯雌酚二磷酸酯
- 中文名称：
- 乙烯雌酚二磷酸酯
- 中文别名：
- 乙烯雌酚二磷酸酯;
磷雌酚
- 英文名称：
- alpha,alpha-diethyl-,bis(dihydrogenphosphate),(e)-4-stilbenediol
- 英文别名：
- [4-[(E)-4-(4-phosphonooxyphenyl)hex-3-en-3-yl]phenyl] dihydrogen phosphate;
ST52-Asta;
Stilbestrol diphosphate;
Fosfestrolum [INN-Latin];
Phosphestrol;
Diethylstilbestryl diphosphate;
fosfestrol;
3,4-Bis-(4-phosphonooxy-phenyl)-hex-3t-en;
Diethylstilbestrol diphosphate;
Phosphoestrolum;
Honvan;
Desdp;
3,4-bis-(4-phosphonooxy-phenyl)-hex-3t-ene
- CAS No.：
- 522-40-7
- 分 子 式：
-
C18H22O8P2
- 分 子 量：
- 428.31
- 精确分子量：
- 428.07900
- PSA：
- 153.14000
- EINECS：
- 208-328-8
- InChI：
- The Key: NLORYLAYLIXTID-ISLYRVAYSA-N3
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
乙烯雌酚二磷酸酯 物化性质
- 密度：
- 1.433g/cm3
- 沸点：
- 648.7ºC at 760mmHg
- 闪点：
- 346.1ºC
- 折射率：
- 1.609
乙烯雌酚二磷酸酯 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WJ5680000
- CHEMICAL NAME :
- 4,4'-Stilbenediol, alpha,alpha'-diethyl-,
bis(dihydrogen phosphate), (E)-
- CAS REGISTRY NUMBER :
- 522-40-7
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C18-H22-O8-P2
- MOLECULAR WEIGHT :
- 428.34
- WISWESSER LINE NOTATION :
- QPQO&OR DY2&UY2&R DOPQQO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 11 mg/kg/3D-I
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
Blood - change in clotting factors
Skin and Appendages - sweating
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 425 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 630 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - cytological changes (including
somatic cell genetic material)
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 25 nmol/L
- REFERENCE :
- CYTOAN Cytologia. (Japan Pub. Trading Co. (USA), 1255 Howard St., San
Francisco, CA 94103) V.1- 1929- Volume(issue)/page/year: 40,817,1975
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X3653
No. of Facilities: 86 (estimated)
No. of Industries: 1
No. of Occupations: 6
No. of Employees: 9667 (estimated)
No. of Female Employees: 7994 (estimated)
