酒石酸辛弗林
- 中文名称：
- 酒石酸辛弗林
- 中文别名：
- 酒石酸辛弗林;
1-(4-羟基苯基)-2-(甲基氨基)乙醇酒石酸盐
- 英文名称：
- SynephrineL-tartrate
- 英文别名：
- 2,3-dihydroxybutanedioic acid,4-[1-hydroxy-2-(methylamino)ethyl]phenol;
EINECS 240-647-8;
Sympathomim
- CAS No.：
- 67-04-9
- 分 子 式：
-
2(C9H13NO2).C4H6O6
- 分 子 量：
- 484.5
- 精确分子量：
- 317.11100
- PSA：
- 167.55000
- EINECS：
- 200-642-3
- InChI：
- The Key: GOVGCYCBKCCFIR-UHFFFAOYSA-N3
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
酒石酸辛弗林 物化性质
- 沸点：
- 341.1ºC at 760 mmHg
- 闪点：
- 163.4ºC
酒石酸辛弗林 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DO7875000
- CAS REGISTRY NUMBER :
- 67-04-9
- LAST UPDATED :
- 199601
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C9-H13-N-O2.C4-H6-O6
- MOLECULAR WEIGHT :
- 317.33
- WISWESSER LINE NOTATION :
- QR DYQ1M1 & 2 &QVYQYQVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 180,155,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2730 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 180,155,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraduodenal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3050 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 180,155,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 237,171,1959
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3200 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 166,437,1932
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 2087 mg/kg
- SEX/DURATION :
- female 7-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
- REFERENCE :
- AAMLAR Atti della Accademia Medica Lombarda. (c/o Prof. W. Montorsi, Festa
del Perdono 3, Milan, Italy) V.20-29, 1931-40; New series: V.15- 1960-
Volume(issue)/page/year: 25,203,1970
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 1044 mg/kg
- SEX/DURATION :
- female 7-16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- AAMLAR Atti della Accademia Medica Lombarda. (c/o Prof. W. Montorsi, Festa
del Perdono 3, Milan, Italy) V.20-29, 1931-40; New series: V.15- 1960-
Volume(issue)/page/year: 25,203,1970
