青霉素O
- 中文名称：
- 青霉素O
- 中文别名：
- 青霉素O;
阿美西林
- 英文名称：
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-6-[[2-(2-propenylthio)acetyl]amino]-, (2S,5R,6R)-
- 英文别名：
- penicillin O;
Almezillin;
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-prop-2-enylsulfanylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
Almecilina;
Allylmercaptomethylpenicillinic acid;
allylsulfanylmethyl-penicillin;
Penicillin AT;
ALMECILLIN;
Allylthiomethylpenicillin;
Almecillinum;
Penicillin O;
Benzathin-penicillin V;
Allylmercaptomethyl-penicillin;
Almecilline
- CAS No.：
- 87-09-2
- 分 子 式：
-
C13H18N2O4S2
- 分 子 量：
- 330.4
- 精确分子量：
- 330.07100
- PSA：
- 137.31000
- InChI：
- The Key: QULKGELYPOJSLP-WCABBAIRSA-N3
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
青霉素O 物化性质
- 密度：
- 1.41g/cm3
- 沸点：
- 629.8ºC at 760 mmHg
- 闪点：
- 334.7ºC
- 折射率：
- 1.631
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开存放
青霉素O 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XI0100000
- CHEMICAL NAME :
- 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
3,3-dimethyl-7-oxo-6-(((2-propenylthio)
acetyl)amino)-
- CAS REGISTRY NUMBER :
- 87-09-2
- BEILSTEIN REFERENCE NO. :
- 0044307
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H18-N2-O4-S2
- MOLECULAR WEIGHT :
- 330.45
- WISWESSER LINE NOTATION :
- T45 ANV ESTJ CMV1S2U1 F1 F1 GVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Multiple routes
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 35827 ug/kg/6D-I
- TOXIC EFFECTS :
- Vascular - structural changes in vessels
- REFERENCE :
- JOALAS Journal of Allergy. (St. Louis, MO) V.1-47, 1929-71. For publisher
information, see JACIBY. Volume(issue)/page/year: 31,455,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intracerebral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 45 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes
- REFERENCE :
- JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830
Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915-
Volume(issue)/page/year: 34,126,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intracerebral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 6490 ug/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes
- REFERENCE :
- JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830
Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915-
Volume(issue)/page/year: 34,126,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes
- REFERENCE :
- JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830
Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915-
Volume(issue)/page/year: 34,126,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intracerebral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5610 ug/kg
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes
- REFERENCE :
- JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830
Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915-
Volume(issue)/page/year: 34,126,1949
