去甲右美沙芬酒石酸盐
- 中文名称：
- 去甲右美沙芬酒石酸盐
- 中文别名：
- 去甲右美沙芬酒石酸盐;
(+)-3-Hydroxy-N-methylmorphinan (+)-tartrate salt Dextrorphan D-tartrate
- 英文名称：
- Dextrophan tartrate
- 英文别名：
- Dextrorphan tartrate;
17-Methyl-morphinan-3-ol,Lg-Hydrogentartrat;
d-3-Hydroxy-N-methylmorphinan tartrate;
Dextrorphan Tartrate Salt;
Levorphanol tartrate;
1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol tartrate,d;
Dextrophan tartrate;
17-methyl-morphinan-3-ol,Lg-hydrogentartrate
- CAS No.：
- 143-98-6
- 分 子 式：
-
C21H29NO7
- 分 子 量：
- 407.46
- 精确分子量：
- 407.19400
- PSA：
- 138.53000
- MDL：
- MFCD00151495
- InChI：
- The Key: RWTWIZDKEIWLKQ-DYWKTHLTSA-N3
- 危险品标志：
-
Xn
- 风险术语：
-
R22
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
去甲右美沙芬酒石酸盐 物化性质
- 沸点：
- 410.4ºC at 760 mmHg
- 闪点：
- 207.2ºC
- 蒸汽压：
- 2.55E-07mmHg at 25°C
- 存储条件/存储方法：
−70℃
去甲右美沙芬酒石酸盐 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QD1930000
- CAS REGISTRY NUMBER :
- 143-98-6
- LAST UPDATED :
- 199106
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C17-H23-N-O.C4-H6-O6
- MOLECULAR WEIGHT :
- 407.51
- WISWESSER LINE NOTATION :
- T6 G666/FQ 2AF Q FX ONT&TTJ IQ O &622 QVYQYVQ -D &621
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 109,189,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 109,189,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 385 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 109,189,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 109,189,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 42 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 31ZPAG "Synthetic Analgesics," Oxford, Pergamon Press, 1966
Volume(issue)/page/year: 2,77,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17414 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 145,11,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 27500 ug/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Behavioral - rigidity (including catalepsy)
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 109,189,1953
去甲右美沙芬酒石酸盐 分子结构与计算化学数据
计算化学数据
1.疏水参数计算参考值（XlogP）:无
2.氢键供体数量:5
3.氢键受体数量:8
4.可旋转化学键数量:3
5.互变异构体数量:3
6.拓扑分子极性表面积139
7.重原子数量:29
8.表面电荷:0
9.复杂度:491
10.同位素原子数量:0
11.确定原子立构中心数量:5
12.不确定原子立构中心数量:0
13.确定化学键立构中心数量:0
14.不确定化学键立构中心数量:0
15.共价键单元数量:2
推荐供应商
湖北恩星生物科技有限公司
去甲右美沙芬酒石酸盐
- 联系人：邵经理
- 电 话：16621771607
- 手 机：16621771607
- Cas号：143-98-6
- 包装：100kg,200kg,300kg,400kg,500kg
- 纯度：
- 价格：64.0元 - 100.0元
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