右吗拉胺
- 中文名称：
- 右吗拉胺
- 中文别名：
- 右吗拉胺;
吗散痛
- 英文名称：
- 1-Butanone,3-methyl-4-(4-morpholinyl)-2,2-diphenyl-1-(1-pyrrolidinyl)-, (3S)-
- 英文别名：
- (3S)-3-methyl-4-morpholin-4-yl-2,2-diphenyl-1-pyrrolidin-1-ylbutan-1-one;
1-((S)-3-Methyl-4-morpholino-2,2-diphenyl-butyryl)-pyrrolidin;
(3S)-3-methyl-4-(morpholin-4-yl)-2,2-diphenyl-1-(pyrrolidin-1-yl)butan-1-one;
Dextromoramidum;
Palfium;
Palphium;
Dextromoramide (BAN);
1-((S)-3-methyl-4-morpholino-2,2-diphenyl-butyryl)-pyrrolidine;
dextromoramide;
Dextromoramida
- CAS No.：
- 357-56-2
- 分 子 式：
-
C25H32N2O2
- 分 子 量：
- 392.53
- 精确分子量：
- 392.24600
- PSA：
- 32.78000
- EINECS：
- 206-613-1
- InChI：
- The Key: INUNXTSAACVKJS-OAQYLSRUSA-N3
- 危险品标志：
-
- 风险术语：
-
- 安全术语：
-
- 分子结构式：
-
- SDS：
- 查看
右吗拉胺 物化性质
- 密度：
- 1.121g/cm3
- 熔点：
- 180-184ºC
- 沸点：
- 579.6ºC at 760mmHg
- 闪点：
- 304.3ºC
- 折射率：
- 1.571
- 存储条件/存储方法：
- 库房通风低温干燥,与食品原料分开存放
右吗拉胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY1055000
- CHEMICAL NAME :
- Pyrrolidine,
1-(2,2-diphenyl-3-methyl-4-morpholinobutyryl)-, (+)-
- CAS REGISTRY NUMBER :
- 357-56-2
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C25-H32-N2-O2
- MOLECULAR WEIGHT :
- 392.59
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 150 ug/kg
- TOXIC EFFECTS :
- Behavioral - coma
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- BMJOAE British Medical Journal. (British Medical Assoc., BMA House,
Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year:
1,211,1959
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 57 ug/kg
- TOXIC EFFECTS :
- Behavioral - coma
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- NYSJAM New York State Journal of Medicine. (Medical Soc. of the State of
New York, POB 5405, Lake Success, NY 11042) V.1- 1901-
Volume(issue)/page/year: 61,83,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 200 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - cyanosis
Gastrointestinal - nausea or vomiting
- REFERENCE :
- PRACAK Practitioner. (Morgan-Grampian Ltd., 40 Beresford St., Woolwich,
London SE18 6BQ, UK) V.1- 1868- Volume(issue)/page/year: 197,348,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 71800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New
York, NY 10003) V.1- 1981- Volume(issue)/page/year: 1,1,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - hypermotility, diarrhea
Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 9,730,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 9,730,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 168 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - hypermotility, diarrhea
Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 9,730,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 17,433,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great
Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949-
Volume(issue)/page/year: 9,730,1957
右吗拉胺 海关数据
中国海关编码：2934999090
- 概述：
- 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
