制备方法

由1,2-丙二醇与环氧丙烷缩合而得。将1,2-丙二醇与环氧丙烷在85%的硫酸作用下进行缩合反应。反应液用氢氧化钠溶液中和,经过滤,减压蒸馏,再在常压下精馏,收集229-233℃馏分即得一缩二丙二醇。原料消耗定额:丙二醇1300kg/t、环氧丙烷1500kg/t、硫酸(98%)100kg/t、烧碱(95%)100kg/t。 精制方法:易含杂质除1,2-丙二醇、三丙二醇之外,尚有少量的水分和酸性物质。一般用减压蒸馏精制。收集中间馏分,用无水硫酸钠干燥后重复进行分馏。

用途简介

用于聚酯树脂的制造。用作乙酸纤维素、硝酸纤维素、虫胶清漆、蓖麻油的溶剂,纤维润滑剂的组分,以及制备增塑剂、熏蒸剂、合成洗涤剂等。此外,二丙二醇可以单独或与二甘醇混合使用,从烃类中萃取芳香烃。

海关代码：

29094919

WGK_Germany：

1
德国有关水污染物质的分类清单

安全说明：

S23-S24/25

RTECS号：

UB8765000

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UB8765000

CHEMICAL NAME :

Propanol, oxybis-

CAS REGISTRY NUMBER :

25265-71-8

LAST UPDATED :

199712

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C6-H14-O3

MOLECULAR WEIGHT :

134.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

14850 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,731,1969

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

>20 mL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,731,1969

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

15 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

50 gm/kg

SEX/DURATION :

female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Maternal Effects - other effects

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB92-196179 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81390 No. of Facilities: 16331 (estimated) No. of Industries: 141 No. of Occupations: 94 No. of Employees: 162532 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81390 No. of Facilities: 22758 (estimated) No. of Industries: 162 No. of Occupations: 137 No. of Employees: 366813 (estimated) No. of Female Employees: 131449 (estimated)

毒理学数据：

1、急性毒性：大鼠口经LD50：14850 mg/kg；兔子皮肤LD50：>20 mL/kg