1,2,3,4-四氢-2-萘胺
- 中文名称：
- 1,2,3,4-四氢-2-萘胺
- 中文别名：
- 1,2,3,4-四氢-2-萘胺;
1,2,3,4-四氢-2-氨基萘
- 英文名称：
- 1,2,3,4-Tetrahydro-2-naphthylamine
- 英文别名：
- 1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE;
1,2,3,4-tetrahydro-1-naphthyl benzoate;
2-R-amino-tetraline;
1,2,3,4-tetrahydronaphthalen-1-yl benzoate;
2-amino-1,2,3,4-tetrahydronaphthalene;
1,2,3,4-tetrahydronaphth-2-ylamine;
1-Benzoyloxy-1.2.3.4-tetrahydro-naphthalin;
1-Naphthalenol,1,2,3,4-tetrahydro-,benzoate;
2-amino-tetralin;
1,2,3,4-tetrahydro-naphth-1-yl benzoate
- CAS No.：
- 2954-50-9
- 分 子 式：
-
C10H13N
- 分 子 量：
- 147.22
- 精确分子量：
- 147.10500
- PSA：
- 26.02000
- EINECS：
- 220-973-7
- InChI：
- InChI=1/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7,11H23
- 危险品标志：
-
- 风险术语：
-
R36/37/38
- 安全术语：
-
S26;S36/37/39
- 分子结构式：
-
- SDS：
- 查看
1,2,3,4-四氢-2-萘胺 物化性质
- 密度：
- 1.023g/cm3
- 沸点：
- 249.6ºC at 760mmHg
- 闪点：
- 110.8ºC
- 折射率：
- 1.561
1,2,3,4-四氢-2-萘胺 安全信息
- 海关代码：
- 2921450090
- 危险类别码：
- R36/37/38
- 安全说明：
- 26-36/37/39
1,2,3,4-四氢-2-萘胺 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QM4900000
- CHEMICAL NAME :
- 2-Naphthylamine, 1,2,3,4-tetrahydro-
- CAS REGISTRY NUMBER :
- 2954-50-9
- BEILSTEIN REFERENCE NO. :
- 1102357
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C10-H13-N
- MOLECULAR WEIGHT :
- 147.24
- WISWESSER LINE NOTATION :
- L66&TJ HZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,466,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,466,1986
** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - sleep
Behavioral - hallucinations, distorted perceptions
- REFERENCE :
- APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und
fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher
information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - sleep
Behavioral - hallucinations, distorted perceptions
- REFERENCE :
- APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und
fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher
information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 64 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon
Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year:
61,168,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Vascular - regional or general arteriolar constriction
Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 35,70,1928
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und
fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher
information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon
Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year:
61,168,1965
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 375 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- APAVAY Virchows Archiv fuer Pathologische, Anatomie und Physiologie, und
fuer Klinische Medizin. (Berlin, Ger.) V.1-343, 1847-1967. For publisher
information, see VAAPB7. Volume(issue)/page/year: 115,14,1889
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
number of implants per female; total number of implants per corpora lutea)
Reproductive - Effects on Newborn - stillbirth
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 100,555,1959
1,2,3,4-四氢-2-萘胺 海关数据
中国海关编码：2921450090
- 概述：
- 2921450090. 1-萘胺和2-萘胺的衍生物及盐(包括1-萘胺）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2921450090 1-naphthylamine (α-naphthylamine), 2-naphthylamine (β-naphthylamine) and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
