1-乙基-3-硝基-1-亚硝基胍
- 中文名称：
- 1-乙基-3-硝基-1-亚硝基胍
- 中文别名：
- 1-乙基-3-硝基-1-亚硝基胍;
N-乙基-Nˊ-硝基-N-亚硝基胍
- 英文名称：
- ENNG
- 英文别名：
- N-ETHYL-N'-NITRO-N-NITROSOGUANIDINE;
N-Nitroso-N'-nitro-N-ethylguanidine;
1-ETHYL-3-NITRO-1-NITROSOGUANIDINE;
1-Ethyl-2-nitro-1-nitrosoguanidine;
N-Nitroso-N-aethyl-N'-nitroguanidin;
N-Aethyl-N'-nitro-N-nitroso-guanidin;
1-ethyl-3-nitro-1-nitroso-guanidin;
N-ethyl-N'-nitro-N-nitroso-guanidine;
1-ETHYL-1-NITROSO-3-NITROGUANIDINE;
ENNG
- CAS No.：
- 4245-77-6
- 分 子 式：
-
C3H7N5O3
- 分 子 量：
- 161.12
- 精确分子量：
- 161.05500
- PSA：
- 114.37000
- EINECS：
- 224-206-7
- InChI：
- The Key: ZGONASGBWOJHDD-UHFFFAOYSA-N3
- 危险品标志：
-
F;
T
- 风险术语：
-
R45;R46;R11;R23R24R25
- 安全术语：
-
S53;S16;S45
- 分子结构式：
-
- SDS：
- 查看
1-乙基-3-硝基-1-亚硝基胍 物化性质
- 密度：
- 1.61g/cm3
- 熔点：
- 118-120ºC (dec.)(lit.)
- 沸点：
- 284.5ºC at 760 mmHg
- 闪点：
- 125.9ºC
- 折射率：
- 1.613
1-乙基-3-硝基-1-亚硝基胍 安全信息
- 包装等级：
- III
- 风险类别：
- 4.1
- 海关代码：
- 2925290090
- 危险类别码：
- 45-46-11-23/24/25
- RTECS号：
- MF2465000
- 危险标志：
- F,T
1-乙基-3-硝基-1-亚硝基胍 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MF2465000
- CHEMICAL NAME :
- Guanidine, 1-ethyl-3-nitro-1-nitroso-
- CAS REGISTRY NUMBER :
- 4245-77-6
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 63
- MOLECULAR FORMULA :
- C3-H7-N5-O3
- MOLECULAR WEIGHT :
- 161.15
- WISWESSER LINE NOTATION :
- WNMYUM&N2&NO
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 504 mg/kg/12W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 55 mg/kg/5W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intrauterine
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Reproductive - Tumorigenic effects - uterine tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 560 mg/kg/4W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 630 mg/kg/21W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Skin and Appendages - tumors
Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 195 mg/kg/37W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 23 mg/kg/35W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Rectal
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1275 mg/kg/23W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - colon tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 2600 mg/kg/48W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 4600 mg/kg/2.2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 1900 mg/kg/33W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 5320 mg/kg/73W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 191 gm/kg/34W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 3000 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6300 mg/kg/63D-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1200 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Rectal
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1440 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - colon tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 2400 mg/kg/34W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3 gm/kg/43W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 560 mg/kg/12W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1500 mg/kg/17W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Gastrointestinal - tumors
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Micronucleus test
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- Sister chromatid exchange
- TYPE OF TEST :
- Sister chromatid exchange
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Mammal - cattle Cells - not otherwise specified
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 194,73,1988
1-乙基-3-硝基-1-亚硝基胍 海关数据
中国海关编码：2925290090
- 概述：
- 2925290090 其他亚胺及其衍生物，以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
F;
T