苄达明
- 中文名称：
- 苄达明
- 中文别名：
- 苄达明;
1-苄基-3-[3-(二甲基氨基)丙氧基]-1H-吲唑
- 英文名称：
- 1-Propanamine,N,N-dimethyl-3-[[1-(phenylmethyl)-1H-indazol-3-yl]oxy]-
- 英文别名：
- 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;
Benzydaminum [INN-Latin];
Benzydamine [INN:BAN];
1H-Indazole,1-benzyl-3-(3-(dimethylamino)propoxy);
Bencidamina [INN-Spanish];
benzidamine;
Benzidamina [DCIT];
EINECS 211-388-8;
C 1523;
Benzydamine;
[3-(1-benzyl-1H-indazol-3-yloxy)-propyl]-dimethyl-amine
- CAS No.：
- 642-72-8
- 分 子 式：
-
C19H23N3O
- 分 子 量：
- 309.40
- 精确分子量：
- 309.18400
- PSA：
- 30.29000
- EINECS：
- 211-388-8
- InChI：
- InChI=1/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H33
- 分子结构式：
-
- SDS：
- 查看
苄达明 物化性质
- 密度：
- 1.08g/cm3
- 沸点：
- 474.4ºC at 760 mmHg
- 闪点：
- 240.7ºC
- 折射率：
- 1.579
- 存储条件/存储方法：
- 通风低温干燥,与库房食品原料分开存放
苄达明 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NK7790000
- CHEMICAL NAME :
- 1H-Indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-
- CAS REGISTRY NUMBER :
- 642-72-8
- BEILSTEIN REFERENCE NO. :
- 0896536
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C19-H23-N3-O
- MOLECULAR WEIGHT :
- 309.45
- WISWESSER LINE NOTATION :
- T56 BNNJ B1R& DO3N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 950 mg/kg
- TOXIC EFFECTS :
- Biochemical - Metabolism (Intermediary) - effect on inflammation or
mediation of inflammation
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 15,41,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 460 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
Gastrointestinal - changes in structure or function of salivary glands
Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 23,1266,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 109 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 15,471,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 445 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1285,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - tremor
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 6,1285,1972
** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8925 mg/kg/21D-I
- TOXIC EFFECTS :
- Liver - changes in liver weight
Kidney, Ureter, Bladder - changes in bladder weight
Related to Chronic Data - changes in testicular weight
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 22,226,1972
苄达明 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
推荐供应商
上海嘉辰化工有限公司
苄达明
- 联系人：孙先生
- 电 话：021-31260639
- 手 机：
- Cas号：642-72-8
- 包装：25
- 纯度：99
- 价格：洽谈
武汉市维斯尔曼生物工程有限公司
苄达明
- 联系人：王明
- 电 话：027-59402396
- 手 机：13419635609
- Cas号：642-72-8
- 包装：25kg,1kg,100g,10g,1g
- 纯度：99%
- 价格：1.0元 - 1.0元
