磷酸可待因,41444-62-6，生产厂家，价格-洛克化工网移动版

磷酸可待因

中文名称：: 磷酸可待因

中文别名：: 磷酸可待因;
4-Hydroxy-2-methylbenzaldehyde;
[4-(Difluoromethoxy)phenyl]acetonitrile;
Isopropoxyaniline;
2-Hydroxy-5-methylpyrimidine;
Metamitron;
3-Hydroxy-alpha-methyl-L-tyrosine sesquihydrate;
Methyl dopa sesquihydrate;
3-hydroxy-alpha-methyl-L-tyrosine hydrate (2:3);
alpha-Methyldopa sesquihydrate;
L-Methyldopa sesquihydrate;
1-hydroxyvitamind3;
7,10(19)-triene-1,3-diol,(1-alpha,3-beta,5z,7e)-10-secocholesta-5;
alfarol;
alpha-hcl;
1-α-hydroxycholecal

英文名称：: CODEINE PHOSPHATE

英文别名：: CODEINE PHOSPHATE;
N-METHYLNORCODEINE HEMIHYDRATE;
CODEINIUM PHOSPHATE HEMIHYDRATE;
CODEINEPHOSPHATE,USP;
Codein phosphate hemihydrate;
MORPHINE-3-METHYL ETHER HEMIHYDRATE

CAS No.：: 41444-62-6

分子式：: C18H24NO7P

分子量：: 397.36

精确分子量：: 415.14000

PSA：: 138.73000

EINECS：: 200-137-8

InChI：: InChI=1/C18H21NO3.H3O4P.H2O/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;1-5(2,3)4;/h3-6,11-13,17,20H,7-9H2,1-2H3;(H3,1,2,3,4);1H2/t11-,12+,13-,17-,18-;;/m0../s13

SDS：: 查看

磷酸可待因制备方法及用途

制备方法

用作镇痛药、镇咳药

用途简介

磷酸可待因物化性质

熔点：: 157.5ºC
沸点：: 462ºC at 760 mmHg
闪点：: 233.2ºC

磷酸可待因 MSDS

Section 1. Chemical Product and Company Identification
    Codeine phosphate        Catalog
    Common Name/
    Number(s).
    Trade Name
    CAS#        41444-62-6
    Manufacturer
    RTECS        QD1310000
    SPECTRUM CHEMICAL MFG. CORP.
    TSCA        TSCA 8(b) inventory: Codeine
    phosphate
    Commercial Name(s)        Not available.
    CI# Not available.
    Synonym        Not available.
    IN CASE OF EMERGENCY
    Not available.
    Chemical Name
    Chemical Family        Not available.        CALL (310) 516-8000
    C18H21NO3.H3PO4.1/2H20
    Chemical Formula
    SPECTRUM CHEMICAL MFG. CORP.

Section 2.Composition and Information on Ingredients
    Exposure Limits
    TWA (mg/m3)        STEL (mg/m3) CEIL (mg/m3)
    Name        CAS #        % by Weight
    1) Codeine phosphate        41444-62-6        100
    Toxicological Data        Codeine phosphate:
    on Ingredients        ORAL (LD50):        Acute: 85 mg/kg [Rat]. 237 mg/kg [Mouse]. 654 mg/kg [Guinea pig].

Section 3. Hazards Identification
    Potential Acute Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant).
    Slightly hazardous in case of skin contact (permeator). Severe over-exposure can result in death.
    Potential Chronic Health        CARCINOGENIC EFFECTS: Not available.
    MUTAGENIC EFFECTS: Not available.
    Effects
    TERATOGENIC EFFECTS: Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in
    one or many human organs.
    Codeine phosphate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,
    keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.
    Skin Contact        After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin
    with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
    Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention.
    Wash contaminated clothing before reusing.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
    medical attention.
    Inhalation        Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
    Serious Inhalation        Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
    waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
    resuscitation. Seek medical attention.
    Ingestion        Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible
    indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen
    tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
    resuscitation. Seek immediate medical attention.
    Serious Ingestion
    Not available.

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.
    Flammable Limits        Not available.
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), phosphates.
    Fire Hazards in Presence of Not available.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    Risks of explosion of the product in presence of static discharge: Not available.
    of Various Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
    Not available.
    Special Remarks on
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container.
    Large Spill        Use a shovel to put the material into a convenient waste disposal container.
    Codeine phosphate

Section 7. Handling and Storage
    Precautions        Keep locked up Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,
    evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not
    breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory
    equipment If ingested, seek medical advice immediately and show the container or the label. Avoid contact with
    skin and eyes
    Storage        Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly
    closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate
    locked safety storage cabinet or room.

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
    Gloves.
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
    BEFORE handling this product.
    Exposure Limits        Not available.

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Powdered solid.)        Odor        Odorless.
    Taste        Not available.
    406.37 g/mole
    Molecular Weight
    Color        White.
    pH (1% soln/water)        Not available.
    Not available.
    Boiling Point
    Melting Point        Not available.
    Not available.
    Critical Temperature
    Specific Gravity        Not available.
    Vapor Pressure        Not applicable.
    Vapor Density        Not available.
    Volatility        Not available.
    Odor Threshold        Not available.
    Water/Oil Dist. Coeff.        Not available.
    Not available.
    Ionicity (in Water)
    Dispersion Properties        See solubility in water, methanol.
    Solubility        Soluble in cold water.
    Partially soluble in methanol.
    Insoluble in diethyl ether.
    Codeine phosphate

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.
    Not available.
    Conditions of Instability
    Not available.
    Incompatibility with various
    substances
    Corrosivity        Non-corrosive in presence of glass.
    Special Remarks on        Not available.
    Reactivity
    Special Remarks on        Not available.
    Corrosivity
    Polymerization        No.

Section 11. Toxicological Information
    Routes of Entry        Eye contact. Inhalation. Ingestion.
    Toxicity to Animals        Acute oral toxicity (LD50): 85 mg/kg [Rat].
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Hazardous in case of skin contact (irritant), of ingestion, of inhalation (lung irritant).
    Humans        Slightly hazardous in case of skin contact (permeator).
    Special Remarks on        Not available.
    Toxicity to Animals
    Special Remarks on        Not available.
    Chronic Effects on Humans
    Special Remarks on other        May Be Habit Forming
    Toxic Effects on Humans

Section 12. Ecological Information
    Ecotoxicity        Not available.
    BOD5 and COD        Not available.
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    arise.
    The products of degradation are more toxic.
    Toxicity of the Products
    of Biodegradation
    Special Remarks on the        Not available.
    Products of Biodegradation
    Codeine phosphate

Section 13. Disposal Considerations
Waste Disposal

Section 14. Transport Information
    DOT Classification        CLASS 6.1: Poisonous material.
    : Alkaloid Salt, Solid, n.o.s.(Codeine Phosphate) : UN1544 PG: III
    Identification
    Not available.
    Special Provisions for
    Transport
    DOT (Pictograms)
    HARMFUL
    STOW AWAY
    FROM
    FOODSTUFFS
    6

Section 15. Other Regulatory Information and Pictograms
    TSCA 8(b) inventory: Codeine phosphate
    Federal and State
    Regulations
    California
    Proposition 65
    Warnings
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
    WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
    Other Classifications
    DSCL (EEC)        R25- Toxic if swallowed.
    R36/37/38- Irritating to eyes,
    respiratory system and skin.
    Health Hazard
    HMIS (U.S.A.)        3 National Fire Protection
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    3 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    6
    Codeine phosphate
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent. Wear appropriate respirator
    when ventilation is inadequate.

SECTION 16 - ADDITIONAL INFORMATION
N/A