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药物化学大辞典
依柏康唑
英文品名 hemoglobin raffimer
名称来源 p-INNList-89,2003;r-INNList-51,2004;
化学表述 the polyaldehyde [(2R,4S,6R,8R,11S,13R)-1,14-dihydroxy-4-hydroxymethyl-3,5,7,10,12-pentaoxatetradecane-2,4,6,8,11,13-hexacarbaldehyde] derived from raffinose [β-D-fructofuranosyl α-D-galactopyranosyl-(1→6)-α-D-glucopyranoside] by treatment with sodium periodate is reacted with human hemoglobin A0 at the 2,3-DPG binding pocket. Both 55% is polymerised.intermolecular and intramolecular crosslinking occurs. This product is reduced to generate covalent amine bonds with >95% crosslinked hemoglobin of which about 55% is polymerised.
CA登记号 197462-97-8
结 构 式
品种类别 血液系统>血液代用品和血浆蛋白成分
ATC编码 B05AA09;
参考文献 MI(4666)
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