产品名称

鲑鱼降钙素

CAS NO

47931-85-1

中文别名

Thyrocalcitonin

英文名称

Calcitonin (salmon)

英文别名

1,2-Dithia-5,8,11,14,17,20-hexaazacyclotricosane,cyclic peptide deriv.;Calciben;Calcimar;Calcitonin (salmon reduced) cyclic(1?;7)-disulfide;Calcitonin (salmonreduced), cyclic (1?;7)-disulfide;Calsyn;Calsynar;Catonin;Karil;L-Prolinamide,L-cysteinyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-a-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-serylglycyl-L-threonyl-,cyclic (1?;7)-disulfide;Miacalcic;Miacalcin;Miadenil;Prontocalcin;Rulicalcin;SMC 021 A/C;Salcatonin;SalmonThyrocalcitonin;Salmon calcitonin;Salmon calcitonin I;Salmoncalcitonin-(1-32);Salmotonin;Stalcin;Tonocalcin;salcitonin;Calcitonin, salmon;? Calcitonin salmon;

分子式

C₁₄₅H₂₄₀N₄₄O₄₈S₂

分子量

3431.85

EINECS

256-342-8

熔点

沸点

毒性

Long-term Storage： -20 ± 5 °C Synonyms： Salcatonin; Salmon Calcitonin; Thyrocalcitonin (salmon) Sequence： H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly -Ser-Gly-Thr-Pro-NH2 acetate salt (Disulfide bond) Fields of Application： Osteoporosis Hypercalcemia Paget’s disease Reflex sympathetic dystrophy (algodistrophy or Sudeck’s disease) Active Substance： In humans, salmon calcitonin is more active than its human analog. Calcitonin (salmon) positively influences bone remodelling and bone mass density due to its inhibiting effect on osteoclast activity. The beneficial effect of salmon calcitonin in the treatment of osteoporotic bone fractures is also due to the promotion of the cartilaginous phase of fracture healing and to pain relief.