产品名称

盐酸司维拉姆

CAS NO

152751-57-0

中文别名

盐酸司维拉姆;2-丙烯-1-胺与环氧氯丙烷的聚合物盐酸盐

英文名称

sevelamer hcl

英文别名

sevelamer hcl;sevelemar;sevelamer hydrochloride;2-propen-1-amine polymer with (chloromethyl)oxirane hydrochloride

分子式

C₆H₁₂NClO

分子量

149.61900

EINECS

682-522-4

熔点

沸点

116.1oC at 760 mmHg

毒性

盐酸司维拉姆 CAS: 152751-57-0 盐酸司维拉姆，药品名称。在新一代磷结合剂的发展上，1998年美国食品卫生检验局 (Food and Drug Administration; FDA) 核准上市的新一代的药品Renagel ﹝sevelamer hydrochloride﹞，是一个相当重要的里程碑。Renagel在药理分类上是全新的药物，其特色为不含铝、不含钙、亦不含任何金属成份的聚分子化合物，病人在三餐同时与药物并服，它以类似树脂交换离子方式吸附肠道中的磷酸，结合后再由粪便排出体外。 sevelamer hydrochloride CAS: 152751-57-0 Hydrochloric acid Victoria division Rahm, drug name. In a new generation of phosphate binder development on 1998, the United States Food Hygiene Inspection Bureau ( Food and Drug Administration; FDA ) approved the listing of a new generation of drugs Renagel, sevelamer hydrochloride, is a quite important milepost. Renagel in pharmacological classification is a new drug, its characteristic is no aluminum, calcium, also does not contain any metallic poly molecular compounds, the patient on meals and drug dose, it in a similar way resin ion exchange adsorption of gut in phosphoric acid, combined with the later by the feces excreted.