产品名称

硝苯地平

CAS NO

21829-25-4

中文别名

利心平;硝苯啶;心痛定;硝苯吡啶

英文名称

3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester

英文别名

3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester (9CI);Corynphar;Depin;Dignokonstant;Dilafed;Dilcor;Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate;Dimethyl 4-(o-Nitrophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate;Dipinkor;Duranifin;Ecodipi;Ecodipin;Ecodipin E;Fedcor;Fedcor Retard;Fedipin;Fenamon;Fenamon SR;Fenihidine;Glopir;Hadipine;Hexadilat;Introcar;Kordafen;Macorel;Megalat;Myogard;NIfedilat;Nedipin;Nicardia;Nicardia retard;Nifangin;Nifar;Nifdemin;Nifebene;Nifecard;Nifecor;Nifedate;Nifedepat;Nifedicor;Nifedin;Nifedine;Nifedipine;Nifedipine retard;Nifedipres;Nifedirex LP;Nifelan;Nifelantern;Nifelat;Nifelat Q;Nifelate;Nifensar XL;Nificard;Nifidine;Nifipen;Niphedipine;Normadil;Novo Nifedin;Nyefax;Nyefax Retard;Orix;Osmo-Adalat;Oxcord;Pidilat;Procardia;ProcardiaXL;Sepamit;Sepamit R;Slofedipine XL;TN 873R;Tensopin;Tibricol;UV-ENP349PINA;Vasdalat;Vasdalat Retard;Vasofed;Xinran;Zenusin;? Nifedipine;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-,dimethyl ester (8CI);2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine;2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic aciddimethyl ester;4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine;Adalat;Adalat 10;Adalat 20;Adalat 5;Adalat CC;Adalat CR;Adalat Crono;Adalat FT;Adalat GITS;Adalat GITS 30;Adalat LA;Adalat LP;Adalat Oros;Adalat PA;Adalat retard;Adalate;Adapine;Adapress;Alat;Aldipin;Alfadat;Alonix;Alonix S;Alpha-Nifedipine Retard;Angipec;Anifed;Anpine;Apo-Nifed;Aprical;BAY 1040;BAY-a 1040;Bonacid;Calcibloc;Calcigard;Calciguard;Calcilat;Camont;Cardifen;Cardilat;Cardilate;Cardionorm;Chronadalate;ChronadalateLP;Citilat;Coracten;Coral;Cordafen;Cordaflex;Cordalat;Cordicant;Cordilan;Cordipin;Corinfar;Corinfar retard;Corotrend;

分子式

C₁₇H₁₈N₂O₆

分子量

346.34

EINECS

244-598-3

熔点

171-175 °C

沸点

475.3oC at 760 mmHg

毒性

高毒

厂家供应硝苯地平21829-25-4 中文名称：硝苯地平 中文别名：利心平；硝苯吡啶；硝苯啶；硝基地平；1,4-二氢-2,6-二甲基-4-(2-硝基苯基)-3,5-吡啶二羧酸二甲酯；心痛定；硝苯地平；硝苯地平(心痛定 英文名称：Nifedipine 英文别名：1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylicaciddime；3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, dimethyl ester；4-(2’-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethy；5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-dim；Adalat CC；bay1040；corinfar；Dimethyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate CAS号：21829-25-4 分子式：C17H18N2O6 分子量：346.34 熔点：171-175oC 水溶解性：<0.1g/100mLat19.5oC 性质：黄色结晶。易溶于丙酮、氯仿、乙酸乙酯，溶于热甲醇，不溶于水。遇光易变质。 用途：长效冠脉扩张药。本品能增加冠脉血流量，减少心肌耗氧量。用于急慢性冠脉功能不全，成其是心绞育及心肌梗塞。 生产方法：将邻硝基苯甲醛、乙酰乙酸甲酯、甲醇、氨水一起回流反应，然后冷冻、结晶，过滤得硝苯地平粗品。粗品用甲醇重结晶即得成品，收率50%。