产品名称

醋酸去氢表雄酮; 去氢表雄酮醋酸酯

CAS NO

853-23-6

中文别名

Prasterone acetate; Dehydroepiandrosterone 3-acetate; Dehydroisoandrosterone acetate; 3b-Hydroxy-5-androstene-17-one acetate

英文名称

Androst-5-en-17-one,3-(acetyloxy)-, (3b)-

英文别名

Androst-5-en-17-one,3b-hydroxy-, acetate (6CI,8CI);17-Oxoandrost-5-en-3b-yl acetate; 3b-Acetoxy-5-androstene-17-one; 3b-Acetoxyandrost-5-en-17-one; 3b-Acetoxydehydroepiandrosterone; 3b-Acetyloxyandrost-5-en-17-one; 3b-Hydroxy-5-androsten-17-oneacetate; 3b-Hydroxy-5-androstene-17-oneacetate; 3b-Hydroxyandrost-5-en-17-one3-acetate; 5-Androsten-3b-ol-17-one acetate; Androstenolone acetate; Dehydroepiandrost-5-en-17-one3-acetate; Dehydroepiandrosterone 3-acetate; Dehydroisoandrosterone 3-acetate;Dehydroisoandrosterone acetate; Prasterone acetate; SKF 2847;trans-Dehydroandrosterone acetate; D5-Dehydroepiandrosterone 3-acetate

分子式

C₂₁H₃₀O₃

分子量

330.47

EINECS

212-714-1

熔点

168-170oC

沸点

434.8oC at 760 mmHg

毒性

醋酸去氢表雄酮853-23-6 中文名称: 醋酸去氢表雄酮 中文同义词: 5-雄甾烯-3β-醇-17-酮-3-醋酸酯;3-羟基-雄甾-5-烯-17-酮-3-醋酸酯;醋酸去氢表雄酮 英文名称: Epiandrosterone acetate 英文同义词: 3-BETA-HYDROXY-5-ALPHA-ANDROSTAN-17-ONE 3-ACETATE; 3-BETA-ACETOXY-5-ALPHA-ANDROSTAN-17-ONE;5-EPIANDROSTER-17-ONE ACETATE; 5-ALPHA-ANDROSTAN-3-BETA-OL-17-ONE ACETATE; 5ALPHA-ANDROSTAN-3BETA-OL-17-ONE 3-ACETATE; ACETIC ACID (3S,5S,8R,9S,10S,13S,14S)-10,13-DIMETHYL-17-OXO-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER; ISOANDROSTERONE ACETATE;EPIANDROSTERONE ACETATE CAS号: 853-23-6 分子式: C21H32O3,C21H30O3 分子量: 332.48,330.46 EINECS号: 212-714-1 用途:避孕药炔诺酮的中间体。用于合成甾体激素药物. 生产方法:将乙醇、盐酸羟胺、吡啶搅拌回流溶解，加入醋酸妊娠双烯醇酮 ，继续回流3h，冷却至5℃，过滤，滤饼用乙醇洗涤，再用温水洗至中性，干燥， 得醋酸妊娠双烯酮肟。然后，将后者与苯、吡啶一起搅拌冷却至0℃左右， 缓缓加入氧氯化磷与苯的混合液，于4-7℃反应3h。再加盐酸水解，在5℃左右保温2h。 静置，分去水层，苯层用水洗涤后进行水蒸汽蒸馏，苯蒸尽后即有淡黄色固体析出， 过滤，水洗至中性，80℃干燥，得去氢表雄酮醋酸酯。