产品名称

伊立替康

CAS NO

97682-44-5

中文别名

联哌喜树碱；伊诺德坎；依列替康

英文名称

Irinotecan

英文别名

[1,4'-Bipiperidine]-1'-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro- 4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]- indolizino[1,2-b]quinolin-9-yl ester;(+)-Irinotecan;Camptosar;(1,4-Bipiperidine)-1-carboxylic acid, 4,11-diethyl-3,4,12-14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3,4:6,7)indolizino(1,2-b)quinolin-9-yl ester, (S)-;Irinotecan base;Irinotecanum [INN-Latin];Irinotecan Hydrochloride;Irrotecan hydrochloride;1,4'-bipiperidine-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinolin -9-yl ester;irinotecan;1,4'-bipiperidine-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester;Irinotecan HCL;Irinotecan(TECANS);irinotecan hydrochloride trihydrate;

分子式

C₃₃H₃₈N₄O₆

分子量

586.69

EINECS

691-567-9

熔点

222-223°

沸点

873.4 °C at 760 mmHg

毒性

盐酸伊立替康（Irinotecan Hydrochloride ）/100 mg) 伊立替康异构体 isomers Irinotecan 伊立替康相关杂质A（Irinotecan Related Compound A）((S)-4-ethyl-4,9-dihydroxy-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione)/10mg 伊立替康杂质BIrinotecan Related Compound B? ((S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione)(10 mg) 伊立替康杂质C Irinotecan Related Compound C (10 mg) ((S)-9-[(1,4''-bipiperidine)-1''-carbonyloxy]-4-methyl-11-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinoline hydrochloride) 伊立替康杂质DIrinotecan Related Compound D (15 mg) ([1,4''-Bipiperidine]-1''-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3'',4'':6,7]indolizino[1,2-b]quinolin-9-yl ester, monohydrochloride, trihydrate, ( R )-)