产品名称

盐酸阿米替林; N,N-二甲基-3-[10,11-二氢-5H-二苯并(a,b)环庚三烯-5-亚基]-1-丙胺盐酸盐

CAS NO

549-18-8

中文别名

3-(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride

英文名称

Amitriptyline hydrochloride

英文别名

1-Propanamine,3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-,hydrochloride (9CI); 5H-Dibenzo[a,d]cycloheptene-D5,g-propylamine,10,11-dihydro-N,N-dimethyl-, hydrochloride (6CI,8CI);10,11-Dihydro-N,N-dimethyl-5H-dibenzo[a,d]cycloheptene-D5,g-propylaminehydrochloride; 5-(3-Dimethylaminopropylidene)dibenzo[a,d][1,4]cycloheptadienehydrochloride; Adepril; Amicen; Amilent; Amilit; Amineurin; Amiplin; Amiprin;Amitid; Amitril; Amitrip; Amitriptyline chloride; Amitriptyline hydrochloride;Amyline; Amyzol; Anapsique; Apo-Amitriptyline; Damilen hydrochloride; Deprex;Domical; Elatrol; Elatrolet; Elavil; Enafon; Endep; Etravil; Euplit; Lantron;Laroxyl; Larozyl; Lentizol; Miketorin; NIH 10794; Noriline; Novoprotect;Pinsanu; Pinsaun; Redomex; Ro 4-1575; Saroten; Saroten Retard; Sarotena;Sarotex; Sylvemid; Syneudon; Teperin; Trepiline; Tridep; Tripta; Triptizol;Trynol; Tryptal; Tryptanol; Tryptine; Tryptizol; Trytomer; Uxen; Vanatrip

分子式

C₂₀H₂₃N.ClH

分子量

313.87

EINECS

208-964-6

熔点

196-197°C

沸点

398.2oC at 760 mmHg

毒性

急性毒性：人类-孩子经口：58mg/kg，昏迷，血压降低不稳，胸、肺、呼吸抑制          人类-成年男性经口：714 ug/kg/1D-I，行为-条件反射改变，心理生理测试值改变            人类-成年男性经口：60 mg/kg/3w-I，嗜睡，共济失调            人类-成年女性经口：10 mg/kg，幻觉            大鼠腹腔LD：

Amitriptyline hydrochloride