- 产品名称
- 曲酸
- CAS NO
- 501-30-4
- 中文别名
- 5-羟基-2-羟甲基-吡喃-4-酮;曲菌酸
- 英文名称
- Kojic acid
- 英文别名
- Kojic acid
- 分子式
- C6H6O4
- 分子量
- 142.11
- EINECS
- 207-922-4
- 熔点
- 152-155°C(lit.)
- 沸点
- 401.7oC at 760 mmHg
- 毒性
- 1、急性毒性:大鼠经静脉LDLo:1gm/kg,除致死剂量外无详细说明;小鼠经口LD50:85mg/kg,行为-嗜睡(普通抑郁活动,惊厥或癫痫,呼吸抑制;小鼠经腹腔LD50:250mg/kg,除致死剂量外无详细说明;小鼠经皮下LDLo:1500mg/kg,行为-嗜睡(普通抑郁活动,惊厥或癫痫,呼吸抑制;小鼠经静脉LD50:1500mg/kg,行为-嗜睡(普通抑郁活动,惊厥或癫痫,呼吸抑制;狗经静脉LD50:1gm/kg,除致死剂量外无详细说明。兔子经静脉LD50:1gm/kg,除致死剂量外无详细说明。2、致突变数据:微生物机体TEST系统突变:细菌-鼠伤寒沙门氏杆菌:2mg/plate;微生
Properties:Kojic Acid is known as 5- hydroxyl -2- hydroxymethyl -1 4- piranone. It is a weak acidicganic compound made by fermentation of microorganisms.Fine tramperic acid is a white yellowish needle like crystal; easily soluble in water, alcohol acetone, slightly soluble in ether, ethyl acetate, chloroform pyridine, insoluble in benzene; its molecular formula is C6H6O4,Molecular weight142.1,Melting point153~156℃。
Key Technical Data
Appearance
|
White off white crystal
|
Assay
|
≥99.0
|
Melting point
|
152~156
|
Loss on drying
|
≤0.5
|
Residue on Ignition
|
≤0.1
|
Heavy Metals
|
≤3
|
Iron
|
≤10
|
Arsenic
|
≤1
|
Chloride
|
≤50
|
Alfatoxin
|
No detectable
|
Applications:It is applied in the field of cosmetics. In the human skin, tyrosine is synthesized by the complex oxidation polymerization of oxygen free radicals under the catalysis of tyrosinase, finally the melanin is synthesized. Kojic Acid can inhibit the synthesis of tyrosinase, so it can strongly inhibit the formation of skin melanin, it is safe non-toxic, will not produce leukoplakia, so Kojic has been added into the make-up water, mask, emulsion, skin cream, can effectively treat freckles, old age spots, pigmentation, acne other whitening cosmetics.20ug/ml.A variety of tyrosinase can be inhibited by the concentration of Kojic Acid 70 to 80% of the vitality is recommended in cosmetics, adding 0.2 to 1%.Kojic Acid is the raw material fproducing maltol ethyl maltol.In pharmaceutical,k\Kojic Acid has no mutagenic effect on eukaryotic cells, it can also eliminate the internal free radicals, enhance the power of the white cell, be beneficial to the health of the human body. Therefore, Kojic Acidhas already been used as the raw material of cephalosporins, the finished product is used to treat the diseases such as headache toothache, the analgesic anti-inflammatory effects are ten Divide the ideal.In agricultural field,it can be used to produce biological pesticides. The bio micro fertilizer (deep red liquid), made of 0.5 to 1% Kojic Acids, is applied to the grain vegetable, whether it is a low concentration as a foliar fertilizer a growth increasing agent froot application.Kojic Acid can also be used as iron analysis reagent, film speckle inhibitor, ect.
- 公司规模
- 11-50人
- 认证信息
-
洛克
- 公司类型
- 贸易商
- 所在地区
- 天津市 天津
- 联系人
- 杨爱英
- 电 话
- 13821082726
- QQ
- 地 址
- 天津