| 中文名 |
吲哚美辛 |
| 中文同义 |
抗炎吲哚酸;茚甲新;1-对氯苯甲酰-5-甲氧基-2-甲基吲哚乙酸;引朵正-乙醯對甲氧基苯胺;消炎痛,吲哚美辛;1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-乙酸;美辛;消炎痛 |
| 英文名 |
Indometacin |
| 英文同义 |
1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;indomethacin crystalline;indomethacin methanol solution;indomethacin usp;AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE |
| CAS |
53-86-1 |
| 分子式 |
C19H16ClNO4 |
| 分子量 |
357.79 |
| EINECS |
200-186-5 |
| 结构式 |
 |
|
性质
|
| 熔点 |
155-162 °C |
| 沸点 |
499.4±45.0 °C(Predicted) |
| 密度 |
1.2135 (rough estimate) |
| 折射率 |
1.6800 (estimate) |
| 储存条件 |
Store at RT |
| 溶解度 |
ethanol: 50 mg/mL, clear, yellow-green |
| 酸度系数(pKa) |
4.5(at 25℃) |
| 形态 |
White to off-white powder |
| 水溶解性 |
Soluble in acetone (40 mg/mL – clear, yellow solution), ethanol (20 mg/mL), ether, castoil; Soluble in chloroform (50 mg/mL – clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral slightly acidic media; insoluble in water. |
| 敏感性 |
Light Sensitive |
| Merck |
14,4968 |
| BRN |
497341 |
| 稳定性 |
Stable. Incompatible with strong oxidizing agents. |
| InChIKey |
CGIGDMFJXJATDK-UHFFFAOYSA-N |
| NIST化学物质信息 |
Indomethacin(53-86-1) |
| EPA化学物质信息 |
Indomethacin (53-86-1) |