产品名称

拉瑞唑来; 甘氨酰甘氨酰-L-缬氨酰-L-亮氨酰-L-缬氨酰-L-谷氨酰胺酰-L-脯氨酰甘氨酸

CAS NO

258818-34-7

中文别名

Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine

英文名称

Glycine,glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-

英文别名

15: PN:US20080103100 SEQID: 15 claimed protein; 15: PN: WO0007609 SEQID: 15 claimedsequence; 15: PN: WO0189551 SEQID: 15 claimed protein; 15: PN: WO2008043107SEQID: 15 claimed protein; 15: PN: WO2008073627 SEQID: 15 claimed protein; 15:PN: WO2009110947 SEQID: 15 claimed sequence; 1: PN: WO0015252 SEQID: 7 claimedprotein; 1: PN: WO2008150981 SEQID: 1 claimed protein; 1: PN: WO2008154493SEQID: 1 claimed protein; 1: PN: WO2009137572 SEQID: 1 claimed protein; 20: PN:WO2007095092 SEQID: 1 claimed sequence; 21: PN: WO2006135811 SEQID: 15 claimedprotein; 24: PN: WO2009006246 SEQID: 15 unclaimed protein; 3: PN: WO2005010022SEQID: 3 claimed sequence; AT 2347; Larazotide

分子式

C₃₂H₅₅N₉O₁₀

分子量

725.83

EINECS

熔点

沸点

毒性

Larazotide/拉瑞唑来是一种八肽，其结构来源于霍乱弧菌分泌的一种蛋白质（小带封闭毒素）。它的氨基酸序列为GGVLVQPG，IUPAC浓缩描述符为H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH，系统名称为甘氨酰-谷氨酰-L-缬氨酸-L-亮氨酸-L-谷氨酰基-L-脯氨酰甘氨酸。Larazotide/拉瑞唑来是细胞旁渗透性的抑制剂。它基于霍乱弧菌肠毒素的合成肽，称为肠带闭塞毒素，可降低肠道通透性。

CAS Number 258818-34-7/881851-50-9 (acetate)

Formula C32H55N9O10

Molar mass 725.845 g·mol