产品名称

TCS PIM-1 1

CAS NO

491871-58-0

中文别名

TCS PIM-1 1

英文名称

6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydro-3-pyridine carbonitrile

英文别名

6-(5-Bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydro-3-pyridine carbonitrile;
TCS PIM-1 1;
2-oxo-4-phenyl-2,5-dihydro-3-furancarbonitrile;
3-cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone;
3-cyano-4-phenyl-2(5H)-furanone;
2-oxo-4-phenyl-2,5-dihydro-furan-3-carbonitrile;
2-oxo-4-phenyl-5H-furan-3-carbonitrile;
3-Cyano-4-phenyl-2(5H)-furanon;
3-Cyan-4-phenyl-2(5H)-furanon

分子式

C18H11BrN2O2

分子量

367.19600

EINECS

熔点

沸点

592.6±50.0 °C(Predicted)

毒性

J&K 2286711 TCS PIM-1 1，是ATP竞争性Pim-1激酶抑制剂, IC50为50nM, 比对Pim-2和MEK1/MEK2的抑制性较高，97%。更多详情欢迎访问百灵威官网www.jkchemical.com，邀请您关注“百灵威”微信公众号。