产品名称

NKH477

CAS NO

138605-00-2

中文别名

NKH477

英文名称

b-Alanine, N,N-dimethyl-,(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-ylester, hydrochloride (1:1)

英文别名

b-Alanine, N,N-dimethyl-,(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-ylester, hydrochloride (9CI); b-Alanine, N,N-dimethyl-,5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-ylester, hydrochloride, [3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]-; 1H-Naphtho[2,1-b]pyran, b-alanine deriv.;6-(3-Dimethylaminopropionyl)forskolin hydrochloride; Adehl; Colforsin dapropatehydrochloride; NKH 477

分子式

C₂₇H₄₃NO₈.ClH

分子量

546.1

EINECS

熔点

沸点

571.4°Cat760mmHg

毒性

  1、急性毒性：大鼠经口LD50：12900μg/kg；大鼠静脉注射LD50：6100μg/kg；狗静脉注射LD50：1600μg/kg；  2、其他多剂量毒性：大鼠静脉注射TDLo：27300μg/kg/13W-I；狗静脉注射TDLo：27300μg/kg/13W-I；  3、生殖毒性：受孕7-17天的大鼠静脉注射TDLo：11mg/kgSEX/DURATION；