产品名称

盐酸阿柔比星

CAS NO

75443-99-1

中文别名

盐酸阿柔比星

英文名称

1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, hydrochloride (1:1), (1R,2R,4S)-

英文别名

1-Naphthacenecarboxylicacid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, hydrochloride, (1R,2R,4S)- (9CI); 1-Naphthacenecarboxylic acid,2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-,methyl ester, hydrochloride, [1R-(1a,2b,4b)]-; Aclacinomycin A hydrochloride; Aclacinon;Aclarubicin hydrochloride

分子式

C₄₂H₅₃NO₁₅.ClH

分子量

848.33

EINECS

熔点

151-153℃

沸点

897.7°C at 760 mmHg

毒性

1、急性毒性：大鼠（口服）LD50： 58,560 μg/kg             大鼠（腹膜）LD50： 17,930 μg/kg             大鼠（皮下）LD50： 20mg/kg             大鼠（静脉）LD50： 25,710 μg/kg             大鼠（肌注）LD50： 37,500 μg/kg