产品名称

左炔诺孕酮

CAS NO

797-63-7

中文别名

D(–)-17α-乙炔基-17β-羟基-18-甲基雌甾-4-烯-3-酮

英文名称

18,19-Dinorpregn-4-en-20-yn-3-one,13-ethyl-17-hydroxy-, (17a)-

英文别名

18,19-Dinor-17a-pregn-4-en-20-yn-3-one,13-ethyl-17-hydroxy- (7CI,8CI); (-)-Norgestrel; 13-Ethyl-17-ethynyl-17b-hydroxy-4-gonen-3-one;13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one; 13-Ethyl-17a-ethynyl-17-hydroxygon-4-en-3-one;13-Ethyl-17a-ethynylgon-4-en-17b-ol-3-one; 13b-Ethyl-17a-ethynyl-17b-hydroxygon-4-en-3-one; 17a-Ethynyl-13-ethyl-19-nortestosterone;17a-Ethynyl-13b-ethyl-3-oxo-4-estren-17b-ol; 17a-Ethynyl-17-hydroxy-18-methylestr-4-en-3-one;17a-Ethynyl-18-homo-19-nortestosterone; 17a-Ethynyl-18-methyl-19-nortestosterone;17b-Hydroxy-18-methyl-19-nor-17a-pregn-4-en-20-yn-3-one; 18-Methyl-17a-ethynyl-19-nortestosterone;18-Methylnorethindrone; 19-Nortestosterone, 17-ethynyl-18-methyl-;D-(-)-Norgestrel; D-Norgestrel; Dexnorgestrel; Femilis; Femilis Slim;Follistrel; Jadelle; Levonorgestrel; Levonova; Lng-IUS; Microlut; Microluton;Microval; Mirena; Norgeston; Norgestrelem; Norlevo; Norplant; Norplant 2;Norplant II; Postinor 2; Wy 5104; d-(17a)-17-Hydroxy-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one

分子式

C₂₁H₂₈O₂

分子量

312.45

EINECS

212-349-8

熔点

206oC

沸点

459.1oC at 760 mmHg

毒性

左炔诺孕酮 左炔诺孕酮 CAS:797-63-7 别名 D-甲炔诺酮 ,左旋甲炔诺酮 炔诺孕酮左旋异构体含量：98%-102% BP USP 细度：粗粉，微粉英文名称：D(minus)-norgestrel CAS NO:797-63-7 质量标准：美国药典25版 鉴别：符合规定 A: 红外吸收 熔点：232℃~ 239℃ 比旋度：-30°~ -35° 干燥失重 ≤ 0.5 % 灼烧残渣：≤0.3% 乙炔化合物限度：7.81%~8.18% 层析杂质： 单个杂质≤0.5% 总杂质≤2.0% 分子量: 312.45 分子式: C21H28O2 别名: D(–)-17α-乙炔基-17β-羟基-18-甲基雌甾-4-烯-3-酮左炔诺孕酮（LNG)为全合成的强效孕激素，是消旋炔诺孕酮的光学活性体，活性比炔诺孕酮强1倍，约为炔诺酮的100倍。为此，剂量比炔诺孕酮可减半，不良反应也减少。左炔诺孕酮主要作用于下丘脑和垂体，使月经中期FSH和LH水平的高峰明显降低或消失，卵巢不排卵，有明显的抗雌激素活性，比炔诺酮强10倍左右，几乎不具有雌激素活性。能使宫颈粘液变稠阻碍精子穿透。对子宫内膜转化显