制备方法

用作粘合剂、防腐涂料,也可用于浇铸工艺用于配制防腐蚀涂料及绝缘漆、粘合剂、层压制品用于涂料工业,制食品罐头涂料、农用喷雾器涂料、矽钢片及漆包线涂料等用于配制防腐蚀涂料及绝缘漆,用作粘合剂、层压材料用于各种材料的粘合,也用作密封材料、层压及浇铸材料、防腐涂料等用作高强度电绝缘材料、光弹性材料、光学仪器粘合剂等用于电气工业大型浇铸、粘合、密封、层压等

用途简介

用途

用作粘合剂、防腐涂料，也可用于浇铸工艺用于配制防腐蚀涂料及绝缘漆、粘合剂、层压制品用于涂料工业，制食品罐头涂料、农用喷雾器涂料、矽钢片及漆包线涂料等用于配制防腐蚀涂料及绝缘漆，用作粘合剂、层压材料用于各种材料的粘合，也用作密封材料、层压及浇铸材料、防腐涂料等用作高强度电绝缘材料、光弹性材料、光学仪器粘合剂等用于电气工业大型浇铸、粘合、密封、层压等

海关代码：

2910900090

危险类别码：

R36/38

安全说明：

28-37/39

RTECS号：

TX3800000

安全标志：

S28:接触皮肤之后，立即使用大量皂液洗涤。
:

危险标志：

Xi: Irritant;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TX3800000

CHEMICAL NAME :

Propane, 2,2-bis(p-(2,3-epoxypropoxy)phenyl)-

CAS REGISTRY NUMBER :

1675-54-3

LAST UPDATED :

199710

DATA ITEMS CITED :

22

MOLECULAR FORMULA :

C21-H24-O4

MOLECULAR WEIGHT :

340.45

WISWESSER LINE NOTATION :

T3OTJ B1OR D- 2X

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Open irritation test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

11300 uL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2200 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

15600 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4 gm/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

1980 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

20 gm/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

166 gm/kg/2Y-I

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

312 gm/kg/2Y-I

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Reproductive - Tumorigenic effects - ovarian tumors

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

312 gm/kg/2Y-I

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Bacteria - Salmonella typhimurium

DOSE/DURATION :

33 ug/plate

REFERENCE :

MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 172,105,1986 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 47,237,1989 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 47,237,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0018 No. of Facilities: 163 (estimated) No. of Industries: 8 No. of Occupations: 10 No. of Employees: 1413 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83440 No. of Facilities: 2505 (estimated) No. of Industries: 54 No. of Occupations: 54 No. of Employees: 32393 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83440 No. of Facilities: 1109 (estimated) No. of Industries: 28 No. of Occupations: 38 No. of Employees: 25257 (estimated) No. of Female Employees: 4341 (estimated)

毒理学数据：

1、急性毒性：大鼠经口腔LD50：11300μl/kg

2、急性毒性：小鼠经口腔LD50： 15600 mg/kg；

3、急性毒性：兔子刺激皮肤LD50： 20 mg/kg

 

生态数据：

通常对水是不危害的，若无政府许可，勿将材料排入周围环境。

中国海关编码：2910900090

概述：

2910900090. 三节环环氧化物，环氧醇（酚，醚），包括其卤化，磺化，硝化或亚硝化的衍生物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途

摘要/Summary：

2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

分子结构数据

1、   摩尔折射率：95.44

2、   摩尔体积（m³/mol）：291.3

3、   等张比容（90.2K）：757.2

4、   表面张力（dyne/cm）：45.6

5、   介电常数（F/m）：无可用

6、   极化率（10^-24cm³）：37.83

计算化学数据

1、   疏水参数计算参考值（XlogP）：4

2、   氢键供体数量：0

3、   氢键受体数量：4

4、   可旋转化学键数量：8

5、   拓扑分子极性表面积（TPSA）：43.5

6、   重原子数量：25

7、   表面电荷：0

8、   复杂度：384

9、   同位素原子数量：0

10、   确定原子立构中心数量：0

11、   不确定原子立构中心数量：2

12、   确定化学键立构中心数量：0

13、   不确定化学键立构中心数量：0

14、   共价键单元数量：1

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  2-双-(4-甘胺氧苯)丙烷红外图谱(IR1)