(2S)-尼古丁氧化物
- 中文名称：
- (2S)-尼古丁氧化物
- 中文别名：
- (2'S)-尼古丁氧化物
- 英文名称：
- Pyridine,3-[(2S)-1-methyl-2-pyrrolidinyl]-, 1-oxide
- 英文别名：
- (2'S)-Nicotine 1-Oxide;
1-chloroacetyl-L-proline;
N-chloroacetyl-L-proline;
nicotine N-oxide;
nicotine nitrogen oxide
- CAS No.：
- 2820-55-5
- 分 子 式：
-
C10H14N2O
- 分 子 量：
- 178.231
- 精确分子量：
- 178.11100
- PSA：
- 28.70000
- InChI：
- The Key: YHXKVHQFWVYXIC-JTQLQIEISA-N3
- 分子结构式：
-
- SDS：
- 查看
(2S)-尼古丁氧化物 物化性质
- 密度：
- 1.15g/cm3
- 沸点：
- 347.9ºC at 760mmHg
- 闪点：
- 164.2ºC
- 折射率：
- 1.589
- 蒸汽压：
- 5.22E-05mmHg at 25°C
(2S)-尼古丁氧化物 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QS9604000
- CHEMICAL NAME :
- Nicotine, 1-oxide
- CAS REGISTRY NUMBER :
- 2820-55-5
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H14-N2-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 295 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 24,534,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 295 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 24,534,1961
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 24100 ug/kg
- TOXIC EFFECTS :
- Behavioral - tremor
Behavioral - muscle contraction or spasticity
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 24,534,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 11,1011,1961
(2S)-尼古丁氧化物 海关数据
中国海关编码：2933990090
- 概述：
- 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
