CAS号：298-51-1
- 中文名称：
- CAS号：298-51-1
- 中文别名：
- CAS号：298-51-1;
10H-Phenothiazine-10-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
- 英文名称：
- 10H-Phenothiazine-10-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
- 英文别名：
- 10H-Phenothiazine-10-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (1:1);
Phenolphthalidin
- CAS No.：
- 298-51-1
- 分 子 式：
-
C19H22N2O2S.ClH
- 分 子 量：
- 378.95
- 精确分子量：
- 378.11700
- PSA：
- 58.08000
- InChI：
- The Key: FOQGDCBIMVXYSR-UHFFFAOYSA-N3
- 安全术语：
- Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, SOx, and HCl. See also ESTERS.
- 分子结构式：
-
- SDS：
- 查看
CAS号：298-51-1 物化性质
- 沸点：
- 469.3ºC at 760 mmHg
- 闪点：
- 237.6ºC
- 折射率：
- 1.612
- 蒸汽压：
- 5.57E-09mmHg at 25°C
CAS号：298-51-1 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SN7350000
- CHEMICAL NAME :
- Phenothiazine-10-carboxylic acid,
2-(diethylamino)ethyl ester, hydrochloride
- CAS REGISTRY NUMBER :
- 298-51-1
- LAST UPDATED :
- 199803
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H22-N2-O2-S.Cl-H
- MOLECULAR WEIGHT :
- 378.95
- WISWESSER LINE NOTATION :
- T C666 BN ISJ BVO2N2&2 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 440 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
13,59,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 140 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
13,59,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 620 mg/kg
- TOXIC EFFECTS :
- Behavioral - sleep
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
13,59,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 90,241,1952
