琥珀酸氯霉素; 氯霉素半琥珀酸酯; 4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸
- 中文名称：
- 琥珀酸氯霉素; 氯霉素半琥珀酸酯; 4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸
- 中文别名：
- CAS号：3544-94-3;
琥珀酸氯霉素;
4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸;
氯霉素半琥珀酸酯
- 英文名称：
- Butanedioic acid,mono[(2R,3R)-2-[(dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propyl] ester
- 英文别名：
- 4-[(2R,3R)-2-[(2,2-dichloroacetyl)amino]-3-hydroxy-3-(4-nitrophenyl)propoxy]-4-oxobutanoic acid;
Levomycetin succinate;
chloramphenicol hemisuccinate;
chloramphenicol succinate;
Chloromycetin succinate;
Chloramphenicol monosuccinate;
Chronicin foam;
CPSA;
chloroamphenicol-3-monosuccinate;
Paraxin succinate;
Kemicetine succinate
- CAS No.：
- 3544-94-3
- 分 子 式：
-
C15H16Cl2N2O8
- 分 子 量：
- 423.20
- 精确分子量：
- 422.02800
- PSA：
- 162.24000
- EINECS：
- 222-590-0
- InChI：
- InChI=1/C15H16Cl2N2O8/c16-14(17)15(24)18-10(7-27-12(22)6-5-11(20)21)13(23)8-1-3-9(4-2-8)19(25)26/h1-4,10,13-14,23H,5-7H2,(H,18,24)(H,20,21)/t10-,13-/m1/s13
- 分子结构式：
-
- SDS：
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琥珀酸氯霉素; 氯霉素半琥珀酸酯; 4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸 物化性质
- 密度：
- 1.536g/cm3
- 沸点：
- 716.3ºC at 760mmHg
- 闪点：
- 387ºC
- 折射率：
- 1.589
- 存储条件/存储方法：
- 库房低温通风干燥
琥珀酸氯霉素; 氯霉素半琥珀酸酯; 4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WM9650000
- CHEMICAL NAME :
- Succinic acid, alpha-monoester with
D-threo-(-)-2,2-dichloro-N-(beta-hydroxy-
alpha-(hydroxymethyl)-p-nitrophenethyl)acetamide
- CAS REGISTRY NUMBER :
- 3544-94-3
- BEILSTEIN REFERENCE NO. :
- 3228488
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C15-H16-Cl2-N2-O8
- MOLECULAR WEIGHT :
- 423.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,135,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 22,1405,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1720 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
France) V.1- 1946- Volume(issue)/page/year: 22,1405,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 11 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,135,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
Italy) V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 9,21,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 4,135,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
Italy) V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 9,21,1954
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
Italy) V.8-43 1953-88 For publisher information, see FRMCE8
Volume(issue)/page/year: 9,21,1954
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 750 mg/kg
- SEX/DURATION :
- female 7-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - behavioral
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H
St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year:
213,238,1981
琥珀酸氯霉素; 氯霉素半琥珀酸酯; 4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸 上游产品
琥珀酸氯霉素; 氯霉素半琥珀酸酯; 4-[2-[(2,2-二氯乙酰)氨基]-3-羟基-3-(4-硝基苯基)丙氧基]-4-氧代丁酸 下游产品
推荐供应商
苏州市晶华化工有限公司
琥珀酸氯霉素
- 联系人：屠先生
- 电 话：0512-52511818
- 手 机：13906222958
- Cas号：3544-94-3
- 包装：2kg
- 纯度：98%-99%
- 价格：洽谈
江苏康祥集团公司
琥珀酸氯霉素
- 联系人：
- 电 话：0511-88424848
- 手 机：
- Cas号：3544-94-3
- 包装：2kg
- 纯度：98%-99%
- 价格：洽谈
