2,2,4-三甲基-1,2-二氢喹啉,147-47-7，生产厂家，价格-洛克化工网移动版

返回



基本信息

物化性质

安全信息

毒理性

结构与计算化学

上游产品

下游产品

表征图谱

2,2,4-三甲基-1,2-二氢喹啉

中文名称：: 2,2,4-三甲基-1,2-二氢喹啉

中文别名：: 2,2,4-三甲基-1,2-二氢喹啉;
1,2-二氢化-2,2,4-三甲基喹啉;
防老剂RD单体

英文名称：: Quinoline,1,2-dihydro-2,2,4-trimethyl-

英文别名：: 1,2-Dihydro-2,2,4-trimethylquinoline;
1,2-hydro-2,2,4-trimethylquinoline;
Quinoline,1,2-dihydro;
2,2,4-Trimethyl-1,2-dihydroquinone;
Trimethyl dihydroquinoline;
2,2,4-trimethyl-1H-quinoline;
2,2,4-trimethyl-[2H]-dihydroquinoline;
2,2,4-Trimethyl-1,2-dihydroquinoline;
2,2,4-trimethyl-quinoline;
2,2,4-TRIMETHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-6-OL;
RALOX TMQ Monomer;
Acetone anil;
TRIMETHYL-1,2-DIHYDROQUINOLINE;
2,2,4-Arimethyl-1H-quinoline

CAS No.：: 147-47-7

分子式：: C₁₂H₁₅N

分子量：: 173.25

精确分子量：: 173.12000

PSA：: 12.03000

EINECS：: 205-688-8

InChI：: The Key: ZNRLMGFXSPUZNR-UHFFFAOYSA-N3

分子结构式：

SDS：: 查看

2,2,4-三甲基-1,2-二氢喹啉毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VB4900000

CHEMICAL NAME :: Quinoline, 1,2-dihydro-2,2,4-trimethyl-

CAS REGISTRY NUMBER :: 147-47-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C12-H15-N

MOLECULAR WEIGHT :: 173.28

WISWESSER LINE NOTATION :: T66 BM CHJ C1 C1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 31(1-3),183,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1450 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 31(1-3),183,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year: 3,93,1976 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg/30D-I

TOXIC EFFECTS :: Liver - liver function tests impaired Related to Chronic Data - death

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 31(2),25,1966

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12500 ug/m3/4H/21W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 9(8),32,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 18200 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thymus weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-456,1997 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 26 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-456,1997 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2990 No. of Facilities: 237 (estimated) No. of Industries: 9 No. of Occupations: 9 No. of Employees: 2135 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2990 No. of Facilities: 190 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 8109 (estimated) No. of Female Employees: 1529 (estimated)