Section 1. Chemical Product and Company Identification
Fluocinonide
Common Name/
Trade Name
Fluocinonide
Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention.
Skin Contact In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get
medical attention.
Serious Skin Contact Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious Inhalation Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. Seek medical attention.
Ingestion If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
attention immediately.
Serious Ingestion Not available.
Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash Points Not available.
Flammable Limits Not available.
Products of Combustion These products are carbon oxides (CO, CO2), halogenated compounds.
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances Non-flammable in presence of shocks.
Explosion Hazards in Presence Slightly explosive in presence of open flames and sparks.
of Various Substances Non-explosive in presence of shocks.
Fire Fighting Media SMALL FIRE: Use DRY chemical powder.
and Instructions LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on When heated to decomposition it emits toxic fumes. As with most organic solids, fire is possible at elevated
Fire Hazards temperatures
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
Hazards explosion hazard.
Section 6. Accidental Release Measures
Small Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill Poisonous solid.
Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition
Fluocinonide
Section 7. Handling and Storage
Precautions Keep locked up.. Keep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe
dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If
ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes.
Storage Keep container tightly closed. Keep container in a cool, well-ventilated area.
Section 8. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spill to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits Not available.
Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid.) Odor Not available.
Taste Not available.
Molecular Weight 494.54 g/mole
Color White.
pH (1% soln/water) Not applicable.
Not available.
Boiling Point
Melting Point 300°C (572°F)
Not available.
Critical Temperature
Specific Gravity Not available.
Vapor Pressure Not applicable.
Vapor Density Not available.
Volatility Not available.
Odor Threshold Not available.
Water/Oil Dist. Coeff. Not available.
Ionicity (in Water) Not available.
Dispersion Properties Not available.
Solubility Insoluble in cold water, hot water.
Soluble in ethanol
Section 10. Stability and Reactivity Data
Stability The product is stable.
Not available.
Instability Temperature
Conditions of Instability Excess heat, dust generation
Incompatibility with various Not available.
substances
Corrosivity Non-corrosive in presence of glass.
Fluocinonide
Special Remarks on Not available.
Reactivity
Special Remarks on Not available.
Corrosivity
Polymerization Will not occur.
Section 11. Toxicological Information
Routes of Entry Absorbed through skin. Dermal contact. Inhalation. Ingestion.
Toxicity to Animals Acute oral toxicity (LD50): 14 mg/kg [Rat].
Chronic Effects on Humans Not available.
Other Toxic Effects on Very hazardous in case of ingestion.
Humans Hazardous in case of skin contact (irritant, permeator), of inhalation.
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on May cause adverse reproductive effects.
Chronic Effects on Humans May affect genetic material (mutagenic)
Special Remarks on other Potential Health Effects:
Toxic Effects on Humans Skin: Skin contact may cause skin irritation witn burning, itching, dryness, Folliculitis, Hypertrichosis, acneform
eruptions, Hypopigmentation, Perioral dermatitis. May also cause allergic contact dermatitis, skin atrophy (loss of
skin collegan), maceration of the skin, secondary infection, Striae, Miliaria. Topical corticosteroids can be
absorbed through the skin in sufficient amounts to produce systemic effects (see ingestion)
Eyes: May cause eye irritaiton, corneal ulcers and visual disturbances
Inhalation: May be harmful if inhaled. It may be irritating to the mucous membranes and upper respiratory tract.
Ingestion: May be fatal if swallowed. It may affect blood (changes is leukocyte count, changes in bone marrow),
and metabolism (weight loss), cardiovascular system (hypertension, cardiac failure). It may also cause edema
Note: Systemic absorption of topical corticosteroids has produced reversible hypothalmic-pituitary-adrenal (HPA)
axid supression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some individuals.
Section 12. Ecological Information
Ecotoxicity Not available.
BOD5 and COD Not available.
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
The products of degradation are as toxic as the product itself.
Toxicity of the Products
of Biodegradation
Special Remarks on the Not available.
Products of Biodegradation
Section 13. Disposal Considerations
Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental
control regulations.
Fluocinonide
Section 14. Transport Information
DOT Classification CLASS 6.1: Poisonous material.
Identification : Toxic solid, organic, n.o.s. (Fluocinonide) UNNA: 2811 PG: II
Not available.
Special Provisions for
Transport
DOT (Pictograms)
Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
California
Proposition 65
Warnings
Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC) R28- Very toxic if swallowed. S22- Do not breathe dust.
R63- Possible risk of harm to the S25- Avoid contact with eyes.
unborn child. S36/37/39- Wear suitable protective clothing,
gloves and eye/face protection.
S45- In case of accident or if you feel unwell,
seek medical advice immediately (show the
label where possible).
Health Hazard
HMIS (U.S.A.) 2 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
2 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
Fluocinonide
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
SECTION 16 - ADDITIONAL INFORMATION
N/A
