茶丙洛尔
- 中文名称：
- 茶丙洛尔
- 中文别名：
- 茶丙洛尔
- 英文名称：
- 1H-Purine-2,6-dione,3,7-dihydro-7-[3-[[2-hydroxy-3-[(2-methyl-1H-indol-4-yl)oxy]propyl]amino]butyl]-1,3-dimethyl-
- 英文别名：
- 7-[3-[[2-hydroxy-3-[(2-methyl-1H-indol-4-yl)oxy]propyl]amino]butyl]-1,3-dimethylpurine-2,6-dione;
Teoprololum [INN-Latin];
Teoprolol;
1H-Purine-2,6-dione,3,7-dihydro-7-(3-((2-hydroxy-3-((2-methyl-1H-indol-4-yl)oxy)propyl)amino)butyl)-1,3-dimethyl;
EINECS 265-600-9;
7-{3-[2-hydroxy-3-(2-methyl-indol-4-yloxy)-propylamino]-butyl}-1,3-dimethyl-3,7-dihydro-purine-2,6-dione;
7-(3-((2-Hydroxy-3-((2-methylindol-4-yl)oxy)propyl)amino)butyl)theophylline;
D-13,312;
Teoprololum
- CAS No.：
- 65184-10-3
- 分 子 式：
-
C23H30N6O4
- 分 子 量：
- 454.59
- 精确分子量：
- 454.23300
- PSA：
- 119.10000
- InChI：
- The Key: HITMZSXZYGLDCV-UHFFFAOYSA-N3
- 安全术语：
- Poison by intravenous route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx.
- 分子结构式：
-
- SDS：
- 查看
茶丙洛尔 物化性质
- 密度：
- 1.37g/cm3
- 沸点：
- 747.6ºC at 760 mmHg
- 闪点：
- 405.9ºC
- 折射率：
- 1.665
茶丙洛尔 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UO8437700
- CHEMICAL NAME :
- 1H-Purine-2,6-dione,
3,7-dihydro-7-(3-((2-hydroxy-3-((2-methyl-1H-indol-4-
yl)oxy)propyl) amino)butyl)-1,3-dimethyl-
- CAS REGISTRY NUMBER :
- 65184-10-3
- BEILSTEIN REFERENCE NO. :
- 1234202
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C23-H30-N6-O4
- MOLECULAR WEIGHT :
- 454.59
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
7,825,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 110 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
7,825,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1870 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
7,825,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 39 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
7,825,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
7,825,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 38 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
7,825,1982
