盐酸脱氧麻黄碱
- 中文名称：
- 盐酸脱氧麻黄碱
- 中文别名：
- 盐酸脱氧麻黄碱;
去氧麻黄碱盐酸盐
- 英文名称：
- methamphetamine hydrochloride
- 英文别名：
- methamphetamine hydrochloride;
deofed;
gerovit;
dexoval;
(+)METHAMPHETAMINE HYDROCHLORIDE;
Metamphetamine hydrochloride;
dextim;
(+)-(S)-methylamphetamine hydrochloride;
destim;
syndrox;
isophen;
metamphetamine*HCl;
d-desoxyephedrine hydrochloride;
adipex;
doxyfed;
desoxyn
- CAS No.：
- 51-57-0
- 分 子 式：
-
C10H16ClN
- 分 子 量：
- 185.69400
- 精确分子量：
- 185.09700
- PSA：
- 12.03000
- EINECS：
- 200-106-9
- InChI：
- The Key: TWXDDNPPQUTEOV-FVGYRXGTSA-N3
- 风险术语：
- R25
- SDS：
- 查看
盐酸脱氧麻黄碱 物化性质
- 熔点：
- 166-168ºC
- 沸点：
- 215.5ºC at 760mmHg
- 闪点：
- 86.8ºC
- 存储条件/存储方法：
- 库房低温,通风,干燥,与食品原料分开存放
盐酸脱氧麻黄碱 安全信息
- 包装等级：
- III
- 风险类别：
- 6.1(b)
- 海关代码：
- 2921499090
- 危险类别码：
- 25
盐酸脱氧麻黄碱 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SH5455000
- CHEMICAL NAME :
- Phenethylamine, N,alpha-dimethyl-, hydrochloride,
(S)-(+)-
- CAS REGISTRY NUMBER :
- 51-57-0
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 13
- MOLECULAR FORMULA :
- C10-H15-N.Cl-H
- MOLECULAR WEIGHT :
- 185.72
- WISWESSER LINE NOTATION :
- 1MY1R &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10930 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 253,466,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,346,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7560 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 87,214,1946
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#02170
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co.,
Steintorst 13, 4010 Basel, Switzerland) V.50- 1920-
Volume(issue)/page/year: 84,351,1954
** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
female 1-21 day(s) after conception
lactating female 19 day(s) post-birth
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria
Reproductive - Tumorigenic effects - transplacental tumorigenesis
- REFERENCE :
- EAGRDS Experimental Aging Research. (Beech Hill Pub. Co., POB 136,
Southwest Harbor, ME 04679) V.1- 1975- Volume(issue)/page/year:
5,509,1979
** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 792 mg/kg
- SEX/DURATION :
- male 4 week(s) pre-mating
female 4 week(s) pre-mating - 3 week(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - biochemical and metabolic
- REFERENCE :
- JONRA9 Journal of Neurochemistry. (Raven Press, 1185 Ave. of the Americas,
New York, NY 10036) V.1- 1956- Volume(issue)/page/year: 20,625,1973
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 80 mg/kg
- SEX/DURATION :
- female 13-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - other effects
Reproductive - Specific Developmental Abnormalities - endocrine system
Reproductive - Effects on Newborn - biochemical and metabolic
- REFERENCE :
- SYNAET Synapse. (Wiley-Liss, Inc., 605 Third Ave., New York, NY USA
10158-0012) V.1- 1987- Volume(issue)/page/year: 15,198,1993
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 17 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- NHOZAX Nippon Hoigaku Zasshi. Japanese Journal of Legal Medicine. (Nippon
Hoi Gakkai, c/o Tokyo Daigaku Igakubu Hoigaku Kyoshitsu, 7-3-1, Hongo,
Bunkyo-ku, Tokyo 113, Japan) V.1- 1944- Volume(issue)/page/year:
46,126,1992
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 19 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
- REFERENCE :
- NHOZAX Nippon Hoigaku Zasshi. Japanese Journal of Legal Medicine. (Nippon
Hoi Gakkai, c/o Tokyo Daigaku Igakubu Hoigaku Kyoshitsu, 7-3-1, Hongo,
Bunkyo-ku, Tokyo 113, Japan) V.1- 1944- Volume(issue)/page/year:
46,126,1992
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X6179
No. of Facilities: 28 (estimated)
No. of Industries: 2
No. of Occupations: 3
No. of Employees: 1579 (estimated)
No. of Female Employees: 1099 (estimated)
盐酸脱氧麻黄碱 海关数据
中国海关编码：2921499090
- 概述：
- 2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
- 申报要素：
- 品名, 成分含量, 用途
- 摘要/Summary：
- 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%