1,1,1,2-四氯乙烷,630-20-6，生产厂家，价格-洛克化工网移动版

1,1,1,2-四氯乙烷

中文名称：: 1,1,1,2-四氯乙烷

中文别名：: 1,1,1,2-四氯乙烷;
1，1，1，2-四氯乙烷;
偏四氯乙烷

英文名称：: Ethane,1,1,1,2-tetrachloro-

英文别名：: 1,1,1,2-tetrachloroethane;
1,1,1,2-Tetrachloroethane;
1,1,1,2-TETRACHLOROETHANE

CAS No.：: 630-20-6

分子式：: C₂H₂Cl₄

分子量：: 167.85

精确分子量：: 165.89100

PSA：: 0.00000

MDL：: MFCD00000807

EINECS：: 211-135-1

BRN：: 1733216

InChI：: The Key: QVLAWKAXOMEXPM-UHFFFAOYSA-N3

风险术语：: R22 R40 R41

安全术语：: S26 S36

分子结构式：

SDS：: 查看

1,1,1,2-四氯乙烷制备方法及用途

制备方法

用作制造药物、虫胶、树脂、蜡和醋酸纤维素等的溶剂及有机合成原料,油脂和生物碱的萃取剂,还用作杀虫剂、除草剂、干洗剂和灭火剂等。

用途简介

用途

用作制造药物、虫胶、树脂、蜡和醋酸纤维素等的溶剂及有机合成原料，油脂和生物碱的萃取剂，还用作杀虫剂、除草剂、干洗剂和灭火剂等。

1,1,1,2-四氯乙烷物化性质

外观与性状：: 无色液体
密度：: 1.598 g/mL at 25 °C(lit.)
熔点：: -68.1ºC
沸点：: 138 °C(lit.)
折射率：: n20/D 1.481(lit.)
存储条件/存储方法：: 库房通风低温干燥,与食品原料分开储运
稳定性相关：: 1、远离强氧化剂、强碱、钾、钠等。
其它信息：: 1.       性状：无色质重油状液体，有类似氯仿的气味。
2.       沸点（ºC,101.3kPa）：130.5
3.       熔点（ºC）：-68.7
4.       相对密度（g/mL,20/4ºC）：1.5406
5.       折射率（n20ºC）：1.4821
6.       黏度（mPa·s,25ºC）：1.38
7.       蒸发热（KJ/kg,b.p.）：207.33
8.       比热容（KJ/(kg·K),18ºC）：0.61
9.       电导率（S/m,25ºC）：2×10^-9
10.    蒸气压（kPa,7.4ºC）：0.67
11.    蒸气压（kPa,19.3ºC）：1.33
12.    蒸气压（kPa,32.1ºC）：2.67
13.    溶解性：能溶于氯代烃、乙醚、甲醇、乙醇等一般有机溶剂中。在水中的溶解度：0℃，20℃，30℃，50℃时分别为0.120%，0.109%，0.115%，0.125%。
14.    相对密度（25℃，4℃）：1.5328
15.   常温折射率（n²⁵）：1.4794
16.   溶度参数(J·cm^-3)^0.5：19.912
17.   van der Waals面积（cm²·mol^-1）：8.550×10⁹
18.   van der Waals体积（cm³·mol^-1）：61.900
19.   液相标准声称热(焓)( kJ·mol^-1)：-193.47
20.   液相标准热熔(J·mol^-1·K^-1)：154.5
21.   气相标准熵(J·mol^-1·K^-1) ：355.96
22.   气相标准热熔(J·mol^-1·K^-1)：102.88

1,1,1,2-四氯乙烷安全信息

包装等级：: II
风险类别：: 6.1(a)
WGK_Germany：: 2
德国有关水污染物质的分类清单
危险类别码：: R22
安全说明：: S26-S36-S45-S24-S16-S7-S39
RTECS号：: KI8450000
安全标志：: S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S36:穿戴合适的防护服装。
危险标志：: Xn: Harmful;

1,1,1,2-四氯乙烷毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI8450000

CHEMICAL NAME :: Ethane, 1,1,1,2-tetrachloro-

CAS REGISTRY NUMBER :: 630-20-6

BEILSTEIN REFERENCE NO. :: 1733216

LAST UPDATED :: 199712

DATA ITEMS CITED :: 32

MOLECULAR FORMULA :: C2-H2-Cl4

MOLECULAR WEIGHT :: 167.84

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 670 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2100 ppm/4H

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1275 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2800 ppm/4H

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 gm/kg/14D-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14 gm/kg/14D-C

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 32500 mg/kg/13W-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16 gm/kg/40D-I

TOXIC EFFECTS :: Behavioral - sleep

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg/3D-I

TOXIC EFFECTS :: Behavioral - sleep Related to Chronic Data - death

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Human Lung

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 369,243,1996 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,87,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 41,87,1986 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 40(3),A46,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 1,1,1,2-TETRACHLOROETHANE-air:Handle with caution REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

毒理学数据：: 毒性及麻醉性比1,1,2,2-四氯乙烷稍低，但为氯仿的3.5倍，四氯化碳的9倍。小鼠腹腔注射LD50：1275mg/kg。

生态数据：

该物质对环境有危害，应特别注意对水体和空气的污染，对大气臭氧层有极强破坏力。

1,1,1,2-四氯乙烷 MSDS

第一部分：化学品名称

1,1,1,2-四氯乙烷分子结构与计算化学数据

分子结构数据

1、摩尔折射率：30.67

2、摩尔体积（cm³/mol）：107.1

3、等张比容（90.2K）：260.5

4、表面张力（dyne/cm）：34.9

5、极化率（10^-24cm³）：12.16

计算化学数据

1.疏水参数计算参考值（XlogP）:2.7

2.氢键供体数量:0

3.氢键受体数量:0

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积0

7.重原子数量:6

8.表面电荷:0

9.复杂度:35.3

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

1,1,1,2-四氯乙烷上游产品

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