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Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
  Product identifiers
    Product name        : Ditalimfos solution    
    Index-No.        : 608-001-00-3    
  Relevant identified uses of the substance or mixture and uses advised against
    Identified uses        : Laboratory chemicals, Manufacture of substances    
  
  

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Section 2. HAZARDS IDENTIFICATION
  Classification of the substance or mixture
  Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
    Flammable liquids (Category 2)
    Acute toxicity, Oral (Category 4)
    Acute toxicity, Inhalation (Category 4)
    Acute toxicity, Dermal (Category 4)
    Eye irritation (Category 2)
  Classification according to EU Directives 67/548/EEC or 1999/45/EC
    Highly flammable. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes.
  Label elements
  Labelling according Regulation (EC) No 1272/2008 [CLP]
    Pictogram
    Signal word        Danger    
    Hazard statement(s)
    H225        Highly flammable liquid and vapour.    
    H302        Harmful if swallowed.    
    H312        Harmful in contact with skin.    
    H319        Causes serious eye irritation.    
    H332        Harmful if inhaled.    
    Precautionary statement(s)
    P210        Keep away from heat/sparks/open flames/hot surfaces. - No smoking.    
    P280        Wear protective gloves/ protective clothing.    
    P305 + P351 + P338        IF IN EYES: Rinse cautiously with water for several minutes. Remove    
    contact lenses, if present and easy to do. Continue rinsing.
    Supplemental Hazard        none    
    Statements
  According to European Directive 67/548/EEC as amended.
    Hazard symbol(s)
    R-phrase(s)
    R11        Highly flammable.    
    R20/21/22        Harmful by inhalation, in contact with skin and if swallowed.    
    R36        Irritating to eyes.    
    S-phrase(s)
    S16        Keep away from sources of ignition - No smoking.    
    S36/37        Wear suitable protective clothing and gloves.    
  Other hazards - none

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
  Mixtures
    Formula        : C12H14NO4PS    
    Molecular Weight        : 299,28 g/mol    
    Component        Classification        Concentration    
  Acetonitrile
    CAS-No.        75-05-8        Flam. Liq. 2; Acute Tox. 4; Eye        -    
    EC-No.        200-835-2        Irrit. 2; H225, H302 + H312 +    
    Index-No.        608-001-00-3        H332, H319    
    Registration number        01-2119471307-38-XXXX    
    F, Xn, R11 - R20/21/22 - R36
    For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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Section 4. FIRST AID MEASURES
  Description of first aid measures
  General advice
    Consult a physician. Show this safety data sheet to the doctor in attendance.
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
  In case of skin contact
    Wash off with soap and plenty of water. Consult a physician.
  In case of eye contact
    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
  If swallowed
    Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
    water. Consult a physician.
  Most important symptoms and effects, both acute and delayed
    Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with proper instructions.,
    The onset of symptoms is generally delayed pending conversion to cyanide., Nausea, Vomiting, Diarrhoea,
    Headache, Dizziness, Rash, Cyanosis, excitement, depression, Drowsiness, impaired judgment, Lack of
    coordination, stupor, death
  Indication of any immediate medical attention and special treatment needed
    no data available

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Section 5. FIREFIGHTING MEASURES
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides, nitrogen oxides (NOx)
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    Use water spray to cool unopened containers.

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Section 6. ACCIDENTAL RELEASE MEASURES
  Personal precautions, protective equipment and emergency procedures
    Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
    Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to
    form explosive concentrations. Vapours can accumulate in low areas.
  Environmental precautions
    Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
  Methods and materials for containment and cleaning up
    Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
    place in container for disposal according to local regulations (see section 13).
  Reference to other sections
    For disposal see section 13.

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Section 7. HANDLING AND STORAGE
  Precautions for safe handling
    Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
    Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
    charge.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
    opened must be carefully resealed and kept upright to prevent leakage.
    Recommended storage temperature: 2 - 8 °C
  Specific end uses
    no data available

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Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
    at the end of workday.
  Personal protective equipment
  Eye/face protection
    Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
    tested and approved under appropriate government standards such as NIOSH (US) or EN
    166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type
    of protective equipment must be selected according to the concentration and amount of the
    dangerous substance at the specific workplace.
  Respiratory protection
    Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
    with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
    to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
    respirator. Use respirators and components tested and approved under appropriate government
    standards such as NIOSH (US) or CEN (EU).

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
  Information on basic physical and chemical properties
    a) Appearance        Form: clear    
    Colour: colourless
    b) Odour        acetone-like    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        no data available    
    point
    f) Initial boiling point and 81,0 - 82,0 °C
    boiling range
    g) Flash point        no data available    
    h) Evaporation rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        Upper explosion limit: 16 %(V)    
    flammability or        Lower explosion limit: 4,4 %(V)    
    explosive limits
    k) Vapour pressure        97,1 hPa at 20 °C    
    l) Vapour density        no data available    
    m) Relative density        0,78 g/cm3 at 20 °C    
    n) Water solubility        soluble    
    o) Partition coefficient: n- log Pow: -0,34
    octanol/water
    p) Autoignition        no data available    
    temperature
    q) Decomposition        no data available    
    temperature
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

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Section 10. STABILITY AND REACTIVITY
  Reactivity
    no data available
  Chemical stability
    no data available
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    Heat, flames and sparks. Extremes of temperature and direct sunlight.
  Incompatible materials
    Acids, Bases, Oxidizing agents, Reducing agents, Alkali metals
  Hazardous decomposition products
    Other decomposition products - no data available

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Section 11. TOXICOLOGICAL INFORMATION
  Information on toxicological effects
  Acute toxicity
    LD50 Oral - rat - 2.460 mg/kg
    LC50 Inhalation - rat - 8 h - 7551 ppm
    Remarks: Behavioral:Altered sleep time (including change in righting reflex). Behavioral:Convulsions or
    effect on seizure threshold. Blood: Hemorrhage.
    LD50 Dermal - rabbit - 2.000 mg/kg
  Skin corrosion/irritation
    Skin - rabbit - Mild skin irritation
  Serious eye damage/eye irritation
    Eyes - rabbit - Irritating to eyes.
  Respiratory or skin sensitization
    Did not cause sensitization on laboratory animals.
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    no data available
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
    no data available
  Specific target organ toxicity - single exposure
    no data available
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Potential health effects
  Inhalation        Harmful if inhaled. May cause respiratory tract irritation.    
  Ingestion        Harmful if swallowed.    
  Skin
    Harmful if absorbed through skin. May cause skin irritation.
  Eyes        Causes eye burns.    
  Signs and Symptoms of Exposure
    Treat as cyanide poisoning., Always have on hand a cyanide first-aid kit, together with proper instructions.,
    The onset of symptoms is generally delayed pending conversion to cyanide., Nausea, Vomiting, Diarrhoea,
    Headache, Dizziness, Rash, Cyanosis, excitement, depression, Drowsiness, impaired judgment, Lack of
    coordination, stupor, death
  Additional Information
    RTECS: Not available

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Section 12. ECOLOGICAL INFORMATION
  Toxicity
    Toxicity to fish        LC50 - Pimephales promelas (fathead minnow) - 1.640,00 mg/l - 96 h    
    Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 3.600,00 mg/l - 48 h
    other aquatic
    invertebrates
    NOEC - Daphnia magna (Water flea) - 640 mg/l - 14 d
  Persistence and degradability
    no data available
  Bioaccumulative potential
    no data available
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    no data available
  Other adverse effects
    no data available

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Section 13. DISPOSAL CONSIDERATIONS
  Waste treatment methods
  Product
    Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting
    as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal
    company.
  Contaminated packaging
    Dispose of as unused product.

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Section 14. TRANSPORT INFORMATION
  UN number
    ADR/RID: 1648        IMDG: 1648        IATA: 1648    
  UN proper shipping name
    ADR/RID: ACETONITRILE, SOLUTION
    IMDG: ACETONITRILE, SOLUTION
    IATA:        Acetonitrile, SOLUTION    
  Transport hazard class(es)
    ADR/RID: 3        IMDG: 3        IATA: 3    
  Packaging group
    ADR/RID: II        IMDG: II        IATA: II    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    no data available

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Section 15. REGULATORY INFORMATION
    This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
  Safety, health and environmental regulations/legislation specific for the substance or mixture
    no data available
  Chemical Safety Assessment
    no data available

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Section 16. OTHER INFORMATION
  Text of H-code(s) and R-phrase(s) mentioned in Section 3
    Acute Tox.        Acute toxicity    
    Eye Irrit.        Eye irritation    
    Flam. Liq.        Flammable liquids    
    H225        Highly flammable liquid and vapour.    
    H302 + H312 +        Harmful if swallowed, in contact with skin or if inhaled    
    H332
    H319        Causes serious eye irritation.    
    F        Highly flammable    
    Xn        Harmful    
    R11        Highly flammable.    
    R20/21/22        Harmful by inhalation, in contact with skin and if swallowed.    
    R36        Irritating to eyes.    
  Further information
    Copyright 2012 Co. LLC. License granted to make unlimited paper copies for internal use
    only.
    The above information is believed to be correct but does not purport to be all inclusive and shall be
    used only as a guide. The information in this document is based on the present state of our knowledge
    and is applicable to the product with regard to appropriate safety precautions. It does not represent any
    guarantee of the properties of the product. Corporation and its Affiliates shall not be held
    liable for any damage resulting from handling or from contact with the above product. See
     and/or the reverse side of invoice or packing slip for additional terms and conditions of sale.