Section I.Chemical Product and Company Identification
Chemical Name Ethyl Glyoxylate Polymer form (47% in Toluene)
Portland OR
Synonym Ethyl Oxoacetate Polymer form;
Glyoxalic Acid Ethyl Ester Polymer form;
Glyoxylic Acid Ethyl Ester Polymer form
Chemical Formula (CH3CH2OCOCHO)n
924-44-7
CAS Number
108-88-3 (Toluene)
Section II. Composition and Information on Ingredients
Chemical Name CAS Number Percent (%) TLV/PEL Toxicology Data
Ethyl Glyoxylate Polymer form (47% in Toluene) 924-44-7 ca. 47.0 This compound is classified as (Toluene)
ca. 53.0 a possible mutagen. There is Rat LD50 (oral) 636 mg/kg
108-88-3
no acceptable exposure limit for Rabbit LD50 (dermal) 14100 µL/kg
(Toluene)
a mutagen. Rat LD50 (inhalation) 49 gm/m3/4H
Section III. Hazards Identification
Acute Health Effects Toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness or death.
Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the
eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Chronic Health Effects CARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Reproductive Effects. (Toluene)
Rat TCLo Inhalation 800 mg/m3/6H, female 14-20 days of pregnancy
TOXIC EFFECTS:
Effects on Embryo or Fetus - Fetotoxicity
Effects on Newborn - Behavioral
Mouse TCLo Inhalation 400 ppm/7H, female 7-16 days of pregnancy
TOXIC EFFECTS:
Specific Developmental Abnormalities - Musculoskeletal system
Effects on Newborn - Biochemical and metabolic
MOUSE TDLo Oral 9 gm/kg, female 6-15 days of pregnancy
TOXIC EFFECTS:
Effects on Embryo or Fetus - Fetal death
Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or
many human organs.
Section IV. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical attention.
Skin Contact In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
Inhalation If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
improve.
Ingestion INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic
material was ingested; the absence of such signs, however, is not conclusive.
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Ethyl Glyoxylate Polymer form (47% in Toluene)
Section V. Fire and Explosion Data
535°C (995°F) (Toluene)
Flammability Flammable. Auto-Ignition
Flammable Limits LOWER: 1.2% UPPER: 7% (Toluene)
Flash Points 7°C (44.6°F)
4°C (39.2°F) (Toluene)
These products are toxic carbon oxides (CO, CO2).
Combustion Products
Fire Hazards Not available.
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media Flammable liquid.
SMALL FIRE: Use DRY chemical powder.
and Instructions
LARGE FIRE: Use alcohol foam, water spray or fog.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Section VI. Accidental Release Measures
Spill Cleanup Flammable material. Toxic material. Irritating material. Possibly mutagenic material. Air sensitive material.
Keep away from heat. Mechanical exhaust required. Stop leak if without risk. Absorb with DRY earth, sand or other
Instructions
non-combustible material. DO NOT get water inside container. DO NOT touch spilled material. Use water spray to reduce
vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Consult federal, state, and/or local
authorities for assistance on disposal.
Section VII. Handling and Storage
FLAMMABLE. TOXIC. IRRITANT. POSSIBLE MUTAGEN. AIR SENSITIVE. STORE UNDER ARGON. Keep locked up.
Handling and Storage
Keep away from heat. Mechanical exhaust required. Avoid excessive heat and light. DO NOT ingest. Do not breathe
Information
gas/fumes/ vapor/spray. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the
container or the label. Treat symptomatically and supportively.
Always store away from incompatible compounds such as oxidizing agents.
Section VIII. Exposure Controls/Personal Protection
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective
Engineering Controls
threshold limit value. Ensure that eyewash station and safety shower is proximal to the work-station location.
Splash goggles. Lab coat. Vapor respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid
Personal Protection
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this
product.
Exposure Limits This compound is classified as a possible mutagen. There is no acceptable exposure limit for a mutagen.
Section IX. Physical and Chemical Properties
Liquid. (Clear, light yellow.) Solubility
Physical state @ 20°C Not available.
1.03
Specific Gravity
0.865 (Toluene)
Molecular Weight (CH3CH2OCOCHO)n Partition Coefficient LOG Kow: 2.73 (Toluene)
C7H8 = 92.14 (Toluene)
Boiling Point 110°C (230°F) Vapor Pressure 3.8 kPa (@ 25°C) (Toluene)
Melting Point -93°C (-135.4°F) (Toluene) Vapor Density 3.1 (Air = 1) (Toluene)
1.48 Not available.
Refractive Index Volatility
1.50 (Toluene)
Critical Temperature Not available. Odor Characteristic.
0.778 cP (@ 0°C) (Toluene) Not available.
Viscosity Taste
Section X. Stability and Reactivity Data
Stability
This material is stable if stored under proper conditions. (See Section VII for instructions)
Conditions of Instability Avoid excessive heat and light.
Incompatibilities Reactive with oxidizing agents.
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Ethyl Glyoxylate Polymer form (47% in Toluene)
Section XI. Toxicological Information
RTECS Number XS5250000 (Toluene)
Eye Contact. Ingestion. Inhalation.
Routes of Exposure
Toxicity Data (Toluene)
Rat LD50 (oral) 636 mg/kg
Rabbit LD50 (dermal) 14100 µL/kg
Rat LD50 (inhalation) 49 gm/m3/4H
Chronic Toxic Effects CARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Reproductive Effects. (Toluene)
Rat TCLo Inhalation 800 mg/m3/6H, female 14-20 days of pregnancy
TOXIC EFFECTS:
Effects on Embryo or Fetus - Fetotoxicity
Effects on Newborn - Behavioral
Mouse TCLo Inhalation 400 ppm/7H, female 7-16 days of pregnancy
TOXIC EFFECTS:
Specific Developmental Abnormalities - Musculoskeletal system
Effects on Newborn - Biochemical and metabolic
MOUSE TDLo Oral 9 gm/kg, female 6-15 days of pregnancy
TOXIC EFFECTS:
Effects on Embryo or Fetus - Fetal death
Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or many
human organs.
Toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness or death.
Acute Toxic Effects
Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the eye
is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or,
occasionally, blistering.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Section XII. Ecological Information
Not available.
Ecotoxicity
Environmental Fate Toluene is released into the atmosphere principally from the volatilization of petroleum fuels and toluene-based solvents and
thinners and from motor vehicle exhaust. Toluene’s production and use as an intermediate in the production of benzoic acid,
benzaldehyde, benzene, explosives, dyes and many other organic compounds may also result in its release to the
environment through various waste streams. Toluene has been detected in emissions from volcanos, forest fires and crude
oil. If released to air, a vapor pressure of 28.4 mm Hg at 25 deg C indicates toluene will exist solely as a vapor in the ambient
atmosphere. Vapor-phase toluene will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl
radicals; the half-life for this reaction in air is estimated to be 3 days. Toluene may also be degraded in the atmosphere by
reaction with nitrate radicals and ozone molecules, but these reactions are too slow to be environmentally important. If
released to soil, toluene is expected to have high to moderate mobility based upon Koc values in the range of 37-178.
Volatilization from moist soil surfaces is expected to be an important fate process based upon a Henry’s Law constant of
6.64X10-3 atm-cu m/mole. Toluene may volatilize from dry soil surfaces based upon its vapor pressure. Biodegradation is
expected to occur rapidly in soil surfaces, with half-lives in the range of several hours to 71 days. If released into water,
toluene is not expected to adsorb to suspended solids and sediment based upon a Koc of 166 measured in lake sediment.
Biodegradation is expected to occur rapidly in water, with reported half-lives of and 56 days in aerobic and anaerobic water,
respectively. Volatilization from water surfaces is expected to be an important fate process based upon this compound’s
Henry’s Law constant. Estimated volatilization half-lives for a model river and model lake are 1 hour and 4 days, respectively.
Measured BCF values of 13 and 90 in fish suggest bioconcentration in aquatic organisms is low to moderate. Hydrolysis is
not expected to be an important environmental fate process for toluene due to lack of hydrolyzable functional groups.
Exposure to toluene may occur occupationally during its production or subsequent use, particularly as a solvent or in gasoline,
via dermal and respiratory routes. The main route of exposure for the general population will be through inhalation from
contaminated air and handling of gasoline as well as ingestion of contaminated drinking water and food, and exposure to
some consumer products.
Section XIII. Disposal Considerations
Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a
Waste Disposal
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state and local regulations when disposing of the substance.
Section XIV. Transport Information
DOT CLASS 3: Flammable liquid
DOT Classification
PIN Number
Proper Shipping Name Toluene, solution
Packing Group (PG) II
DOT Pictograms
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Ethyl Glyoxylate Polymer form (47% in Toluene)
Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This compound is ON the EPA Toxic Substances Control Act (TSCA) inventory list.
(EPA)
WHMIS Classification CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
(Canada)
On NDSL.
On DSL. (Toluene)
EINECS Number (EEC) 213-105-3
203-625-9 (Toluene)
EEC Risk Statements R11- Highly flammable.
R18- In use, may form flammable/explosive vapor-air mixture.
R23/24/25- Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38- Irritating to eyes, respiratory system and skin.
R46- May cause heritable genetic damage.
R47- May cause birth defects.
SECTION 16 - ADDITIONAL INFORMATION
N/A
