Section I.Chemical Product and Company Identification
Chemical Name Phenylmagnesium Iodide
(42% in Ethyl Ether, ca. 2mol/L)
Portland OR
Synonym Magnesium, Iodophenyl- (9 CI)
Chemical Formula C6H5MgI
CAS Number 16002-63-4
60-29-7 (Ethyl Ether)
Section II. Composition and Information on Ingredients
CAS Number Percent (%) TLV/PEL Toxicology Data
Chemical Name
Phenylmagnesium Iodide 42.0 Not available. Ethyl Ether:
16002-63-4
(42% in Ethyl Ether, ca. 2mol/L)
60-29-7 (Ethyl 58.0 Rat LD50 (oral) 1215mg/kg
Rabbit LD50 (dermal) >20ml/kg
Ether)
Mouse LC50 (inhalation)
31000ppm/30M
Section III. Hazards Identification
Acute Health Effects Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous
membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal
damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by
coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested.
Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Chronic Health Effects CARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or
prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial
infection.
Section IV. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical attention.
Skin Contact In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing
before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Inhalation If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
improve.
Ingestion DO NOT INDUCE VOMITING. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing,
perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a
possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive.
Continued on Next Page
Phenylmagnesium Iodide
(42% in Ethyl Ether, ca. 2mol/L)
Section V. Fire and Explosion Data
Auto-Ignition 160°C (320°F) (Ethyl Ether)
Flammability Flammable.
Flash Points Flammable Limits Not available.
-40°C (-40°F) (Ethyl Ether).
Combustion Products These products are toxic carbon oxides (CO, CO 2). Some metallic oxides.
Fire Hazards
Not available.
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media
Flammable liquid.
SMALL FIRE: Use DRY chemical powder.
and Instructions
LARGE FIRE: Use alcohol foam, water spray or fog.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Section VI. Accidental Release Measures
Spill Cleanup Water-reactive material. Flammable material. Corrosive material. Harmful material. May form explosive peroxides. Air,
heat, and light sensitive material. Do not distill to dryness. Refrigerate material.
Instructions
Keep away from heat. Mechanical exhaust required. Stop leak if without risk. Absorb with DRY earth, sand or other
non-combustible material. DO NOT get water inside container. DO NOT touch spilled material. Use water spray curtain
to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Consult federal, state,
and/or local authorities for assistance on disposal.
Section VII. Handling and Storage
Handling and Storage WATER-REACTIVE. FLAMMABLE. CORROSIVE. HARMFUL. MAY FORM EXPLOSIVE PEROXIDES. AIR, HEAT,
AND LIGHT SENSITIVE. DO NOT DISTILL TO DRYNESS. REFRIGERATE. Keep under inert atmosphere. Keep
Information
container dry. Do not breathe gas/fumes/ vapor/spray. Never add water to this product. Wear suitable protective
clothing. If you feel unwell, seek medical attention and show the label when possible. Treat symptomatically and
supportively.
Always store away from incompatible compounds such as oxidizing agents, acids.
Section VIII. Exposure Controls/Personal Protection
Engineering Controls Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash station and safety shower is proximal to the work-station location.
Personal Protection Face shield. Lab coat. Vapor respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Exposure Limits Not available.
Section IX. Physical and Chemical Properties
Physical state @ 20°C Liquid. Solubility
Ethyl Ether:
Miscible with lower aliphatic alcohols,
Specific Gravity Not available. benzene, chloroform, petroleum ether, fat
solvents, many oils, most organic
solvents.
Soluble in concentrated hydrochloric acid,
acetone, solvent naphtha.
Very soluble in ethanol, ethyl ether.
In water, 6.04X10+4mg/L @ 25°C.
Molecular Weight 228.31 Partition Coefficient Not available.
Boiling Point 34.6°C (94.3°F) (Ethyl Ether) Vapor Pressure 59 kPa (@ 20°C) (Ethyl Ether)
Melting Point -116°C (-176.8°F) (Ethyl Ether) Vapor Density 2.6 (Air = 1) (Ethyl Ether)
1.3526 @ 20°C (Ethyl Ether) Volatility Not available.
Refractive Index
Critical Temperature Odor Ether-like.
Not available.
Dynamic: 0.2448 cP (Ethyl Ether) Burning and sweet.
Viscosity Taste
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Phenylmagnesium Iodide
(42% in Ethyl Ether, ca. 2mol/L)
Section X. Stability and Reactivity Data
Stability
This material is stable if stored under proper conditions. (See Section VII for instructions)
Conditions of Instability Heat and light accelerate peroxide formation. Avoid excessive heat and light.
Incompatibilities
Reactive with oxidizing agents, strong acids.
The product REACTS violently with water to emit FLAMMABLE BUT NON TOXIC GASES.
Section XI. Toxicological Information
RTECS Number KI5775000 (Ethyl Ether)
Eye Contact. Ingestion. Inhalation. Skin contact.
Routes of Exposure
Toxicity Data Ethyl Ether:
Rat LD50 (oral) 1215mg/kg
Rabbit LD50 (dermal) >20ml/kg
Mouse LC50 (inhalation) 31000ppm/30M
CARCINOGENIC EFFECTS : Not available.
Chronic Toxic Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or
prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
Acute Toxic Effects Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous
membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal
damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by
coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested.
Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Section XII. Ecological Information
Ecotoxicity Not available.
Environmental Fate Ethyl Ether:
Diethyl ether's production and use as a solvent, in the manufacture of gun powder, and as a primer for gasoline engines
may result in its release to the environment through various waste streams. If released
to air, a vapor pressure of 538 mm Hg at 25 deg C indicates diethyl ether will exist solely as a vapor in the ambient
atmosphere. Vapor-phase diethyl ether will be degraded in the atmosphere by reaction with photochemically-produced
hydroxyl radicals and nitrate radicals; half-lives for these reactions in air are estimated to be 1.2 and 5.8 days,
respectively. Direct photolysis is not expected to be an important removal process since aliphatic ethers do not absorb
light in the environmental spectrum. If released to soil, diethyl ether is expected to have high mobility based upon an
estimated Koc of 73. Volatilization from moist soil surfaces is expected to be an important fate process based upon a
Henry's Law constant of 1.23X10-3 atm-cu m/mole. Diethyl ether is expected to volatilize from dry soil surfaces based
upon its vapor pressure. Aqueous screening studies indicate biodegradation is expected to be a slow fate process in both
soil and water; 0 to 1.1% BODT was observed over a period of 5 days. If released into water, diethyl ether is not
expected to adsorb to suspended solids and sediment in water based upon the estimated Koc. Volatilization from water
surfaces is expected to be an important fate process based upon this compound's Henry's Law constant. Estimated
volatilization half-lives from a model river and model lake are 3.1 hours and 3.6 days, respectively. BCFs ranging from 0.9
to 9.1 in carp suggest bioconcentration in aquatic organisms is low. Hydrolysis is not expected to occur due to the lack of
hydrolyzable functional groups. Occupational exposure to diethyl ether may occur through inhalation and dermal contact
with this compound at workplaces where diethyl ether is produced or used. The general population may be exposed to
diethyl ether from consumer products, inhalation of ambient air, and ingestion of contaminated drinking water. (HSDB)
Section XIII. Disposal Considerations
Waste Disposal Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state and local regulations when disposing of the substance.
Section XIV. Transport Information
DOT Classification CLASS 4.3: Dangerous when wet material.
CLASS 3: Flammable liquid.
PIN Number
Proper Shipping Name
Organometallic substance, liquid, water-reactive, flammable
Packing Group (PG) I
DOT Pictograms
DANGEROUS WHEN
WET
4
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Phenylmagnesium Iodide
(42% in Ethyl Ether, ca. 2mol/L)
Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40
CFR 720.36 (C) for those products not on the inventory list:
(EPA)
(i) These products are supplied solely for use in research and development by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
supplied on an MSDS sheet.
WHMIS Classification CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).
CLASS E: Corrosive liquid.
(Canada)
EINECS Number (EEC) 200-467-2 (Ethyl Ether)
EEC Risk Statements
R12- Extremely flammable.
R14- Reacts violently with water.
R19- May form explosive peroxides.
R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.
R34- Causes burns.
SECTION 16 - ADDITIONAL INFORMATION
N/A
