3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶
- 中文名称：
- 3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶
- 中文别名：
- 3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶;
5-羟基-4-甲氧甲基-6-甲基-3-吡啶甲醇;
3-羟基-5-羟基甲基-4-甲氧基甲基-2-甲基吡啶
- 英文名称：
- 3-Pyridinemethanol,5-hydroxy-4-(methoxymethyl)-6-methyl-
- 英文别名：
- 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol;
3-Pyridinemethanol,5-hydroxy-4-(methoxymethyl)-6-methyl;
4-Methoxymethylpyridoxine;
3-HYDROXY-5-HYDROXYMETHYL-4-METHOXYMETHYL-2-METHYLPYRIDINE;
5-Hydroxy-4-(methoxymethyl)-6-methyl-3-pyridinemethanol;
4'-O-methyl pyridoxine;
5-hydroxymethyl-4-methoxymethyl-2-methyl-pyridin-3-ol;
Ginkgotoxin;
4-Methoxypyridoxine;
4'-O-methyl pyridoxime
- CAS No.：
- 1464-33-1
- 分 子 式：
-
C9H13NO3
- 分 子 量：
- 183.21
- 精确分子量：
- 183.09000
- PSA：
- 62.58000
- InChI：
- The Key: SVINQHQHARVZFF-UHFFFAOYSA-N3
- 分子结构式：
-
- SDS：
- 查看
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 制备方法及用途
制备方法
用甲氧基乙酰丙酮与氰乙酸乙酯在氢氧化铵参与下环合,生成5-氰基-6-羟基-4-甲氧甲基-2-甲基吡啶,然后硝化得5-氰基-6-羟基-4-甲氧甲基-2-甲基-3-硝基吡啶,氯化得6-氯-5-氰基-4-甲氧甲基-2-甲基-3-硝基吡啶,以钯碳催化氢化得3-氨基-5-氨甲基-4-甲氧甲基-2-甲基吡啶,最后氨基重氮化并水解制得该品。
用途简介
维生素B6的中间体。
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 物化性质
- 沸点：
- 404.2ºC at 760mmHg
- 闪点：
- 198.3ºC
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 安全信息
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT5009000
- CHEMICAL NAME :
- 3-Pyridinemethanol,
5-hydroxy-4-(methoxymethyl)-6-methyl-
- CAS REGISTRY NUMBER :
- 1464-33-1
- BEILSTEIN REFERENCE NO. :
- 0150788
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C9-H13-N-O3
- MOLECULAR WEIGHT :
- 183.23
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 540 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 23 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 9 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
(Princeton, NJ 08540) V.1-15, 1963-74. For publisher information, see
PESTD5. Volume(issue)/page/year: 4,179,1964
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 海关数据
中国海关编码：2933399090
- 概述：
- 2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
- 申报要素：
- 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
- 摘要/Summary：
- 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 上游产品
3-羟基-5-羟甲基-4-甲氧甲基-2-甲基吡啶 下游产品
