代森锌,12122-67-7，生产厂家，价格-洛克化工网移动版

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基本信息

制备方法及用途

物化性质

安全信息

毒理性

MSDS

海关数据

结构与计算化学

上游产品

表征图谱

代森锌

中文名称：: 代森锌

中文别名：: 代森锌;
培金;
2-(4-氯苯基)苯基乙酰基)-1H-茚-1,3(2H)-二酮;
乙撑双二硫代氨基甲酸锌;
氯鼠酮;
亚乙基双(二硫代氨基甲酸)锌;
1,2-亚乙基两个氨荒酸锌

英文名称：: Zineb

英文别名：: Zinc, [N-[2-[(dithiocarboxy)amino]ethyl]carbamodithioato(2-)-κS,κS']-;
Zinc, [[1,2-ethanediylbis[carbamodithioato]](2-)]-;
Zinc, [[2-[(dithiocarboxy)amino]ethyl]carbamodithioato(2-)-κS,κS']- (9CI);
Zinc, [ethylenebis[dithiocarbamato]]- (8CI);
Carbamodithioic acid, 1,2-ethanediylbis-, zinc complex;
[N-[2-[(Dithiocarboxy)amino]ethyl]carbamodithioato(2-)-κS,κS']zinc;
Aaphytora;
Aphytora;
Aspor;
Aspor C;
Asporum;
Azzurro;
Blizene;
Bonzeb;
Bonzeb 10;
Carbadine;
Carbamodithioic acid, 1,2-ethanediylbis-, zinc salt;
Crittox;
Curit;
Cynkotox;
Daisen;
Deikusol;
Dipher;
Discon;
Dithane 65;
Dithane Z;
Dithane Z 78;
Ethylenebis[dithiocarbamato]zinc;
Ethylenebis[dithiocarbamic acid] zinc salt;
Fungo-Pulvit;
Funjeb;
Hexathane;
Indofil Z 78;
Lirotan;
Lonacol;
Micide 55;
NSC 49513;
Novozir;
Novozir N;
Novozir N 50;
Parzate zineb;
Perozin;
Perozin 75B;
Perozine;
Perozine 75B;
Phytox;
Pilzol SZ;
Polyram Z;
Thionic M;
Tiezene;
Tritoftorol;
Turbair Zineb Fungicide;
Unizeb;
Zebenide;
Zebtox;
Zinc N,N'-ethylenebisdithiocarbamate;
Zinc ethylenebis[dithiocarbamate];
Zineb;
Zineb 80;
Zinosan

CAS No.：: 12122-67-7

分子式：: C₄H₆N₂S₄Zn

分子量：: 275.76

精确分子量：: 273.87053

PSA：: 88.24000

MDL：: MFCD00067266

EINECS：: 235-180-1

BRN：: 4165797

InChI：: InChI=1/C4H8N2S4.Zn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-1/rC4H6N2S4Zn/c7-3(8)5-1-2-6-4-9-11-10-4/h6H,1-2H2,(H-,5,7,8)/p+13

危险品标志：: Xi

风险术语：: R37;R43;

安全术语：: S8;S24/25;S46;

分子结构式：

SDS：: 查看

代森锌制备方法及用途

制备方法

1.先合成代森钠。可以采用一步法或两步法。两步法有利于控制副产物三硫代碳酸钠的生成,质量好,收率也高。反应温度控制在将5%硫酸溶液缓慢地滴加到上述代森钠水溶液中,中和过量的氢氧化钠和分解副产物三硫代碳酸钠,至pH值6～7,并排除硫代氢气体。将已中和的代森钠水溶液升温加热至40～45℃,在搅拌下加入硫酸锌水溶液,搅拌30min,离心分离,清水洗涤,于93kPa下于50～60℃烘干,得代森锌。 2.由乙二胺、二硫化碳和氢氧化钠在30～35℃下反应生成代森钠,再与氯化锌或硫酸锌反应生成产品。

合成制备方法

1.先合成代森钠。可以采用一步法或两步法。两步法有利于控制副产物三硫代碳酸钠的生成，质量好，收率也高。反应温度控制在<35℃，二硫化碳的滴加速度由反应温度而定。分批加入氢氧化钠溶液，加碱温度控制在35℃左右，每批都控制pH≤9。

将5%硫酸溶液缓慢地滴加到上述代森钠水溶液中，中和过量的氢氧化钠和分解副产物三硫代碳酸钠，至pH值6～7，并排除硫代氢气体。将已中和的代森钠水溶液升温加热至40～45℃，在搅拌下加入硫酸锌水溶液，搅拌30min，离心分离，清水洗涤，于93kPa下于50～60℃烘干，得代森锌。

2.由乙二胺、二硫化碳和氢氧化钠在30～35℃下反应生成代森钠，再与氯化锌或硫酸锌反应生成产品。

用途简介

1.广谱性、保护性杀菌剂。可用于防治水稻、麦类、蔬菜、葡萄、果树、烟草等作物的多种病害,如麦类锈病、玉米大斑病、茶赤星病、烟草立枯病、炭疽病、野大病、花生褐斑病、马铃薯疫病、疮痂病、黑痣病以及苹果、梨、桃、柑橘、葡萄、蔬菜等多种病害。一般用80%可湿性粉剂500～800倍液喷雾。 2.对多种作物具有保护性杀菌作用,是用于叶部的保护性杀菌剂。主要用于防治麦类、水稻、果树、蔬菜和烟草等多种作物的病害。 3.用作硫化促进剂、农用杀虫剂和杀菌剂,有65%及80%可湿性粉末。

用途

1.广谱性、保护性杀菌剂。可用于防治水稻、麦类、蔬菜、葡萄、果树、烟草等作物的多种病害，如麦类锈病、玉米大斑病、茶赤星病、烟草立枯病、炭疽病、野大病、花生褐斑病、马铃薯疫病、疮痂病、黑痣病以及苹果、梨、桃、柑橘、葡萄、蔬菜等多种病害。一般用80%可湿性粉剂500～800倍液喷雾。

2.对多种作物具有保护性杀菌作用，是用于叶部的保护性杀菌剂。主要用于防治麦类、水稻、果树、蔬菜和烟草等多种作物的病害。

3.用作硫化促进剂、农用杀虫剂和杀菌剂，有65%及80%可湿性粉末。^[21]

代森锌毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZH3325000

CHEMICAL NAME :: Zinc, (ethylenebis(dithiocarbamato))-

CAS REGISTRY NUMBER :: 12122-67-7

LAST UPDATED :: 199803

DATA ITEMS CITED :: 54

MOLECULAR FORMULA :: C4-H6-N2-S4.Zn

MOLECULAR WEIGHT :: 275.73

WISWESSER LINE NOTATION :: T9MYS-ZN-SYMTJ BUS FUS

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7600 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1940 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 gm/kg/2W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 30 gm/kg/30D-I

TOXIC EFFECTS :: Endocrine - other changes Endocrine - changes in pituitary weight Endocrine - changes in thyroid weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 gm/kg/2Y-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Endocrine - thyroid weight (goiter) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg/5D-I

TOXIC EFFECTS :: Endocrine - hypoglycemia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 18200 mg/kg/26W-I

TOXIC EFFECTS :: Gastrointestinal - alteration in gastric secretion Liver - liver function tests impaired Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cattle

DOSE/DURATION :: 10800 mg/kg/39W-I

TOXIC EFFECTS :: Endocrine - evidence of thyroid hypofunction Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 53580 mg/kg/94W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Gastrointestinal - colon tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7800 mg/kg/5W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2600 mg/kg/13W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1760 mg/kg female 11-21 day(s) after conception

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 273 gm/kg/2.5Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Endocrine - thyroid tumors Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4 gm/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4 gm/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 8 gm/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4 gm/kg

SEX/DURATION :: female 13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 8 mg/kg

SEX/DURATION :: female 16 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 20 mg/m3/4H

SEX/DURATION :: multigeneration

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 28 gm/kg

SEX/DURATION :: female 6-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: DNA damage

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(1),80,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,245,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,245,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW CNDQA8 Cahiers de Nutrition et de Dietetique. (Editions Meteore, 42, rue du Louvre, 75001 Paris, France) V.1- 1966- Volume(issue)/page/year: 10(3),43,1975 TOXICOLOGY REVIEW CNDQA8 Cahiers de Nutrition et de Dietetique. (Editions Meteore, 42, rue du Louvre, 75001 Paris, France) V.1- 1966- Volume(issue)/page/year: 14,49,1979 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83787 No. of Facilities: 12 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 72 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83787 No. of Facilities: 291 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3205 (estimated)

毒理学数据：

1.急性毒性^[6]

LD50：＞5200mg/kg（大鼠经口）

LC50：1850mg/m³（大鼠吸入）

2.刺激性 暂无资料

3.亚急性与慢性毒性^[7] 长期接触可能有致甲状腺肿作用。

4.致突变性^[8] 微生物致突变：枯草杆菌1000ppm。姐妹染色单体交换：人淋巴细胞10mg/L。DNA抑制：人淋巴细胞10mg/L。细胞遗传学分析：人吸入500μg/m³（7h，3a）（间断性）。微核试验：人淋巴细胞25mg/L（72h）。

5.致畸性^[9] 大鼠孕后13d经口给予最低中毒剂量（TDLo）4g/kg，致颅面部（包括鼻、舌）、肌肉骨骼系统、眼、耳发育畸形。大鼠孕后6~19d经口给予最低中毒剂量（TDLo）28g/kg，致中枢神经系统、肌肉骨骼系统发育畸形。

6.致癌性^[10] IARC致癌性评论：G3，对人及动物致癌性证据不足。

7.其他^[11] 大鼠经口最低中毒剂量（TDLo）：4g/kg（孕后用药13d），对胎鼠中枢神经系统、肌肉骨骼系统、颅面发育有影响。

生态数据：

1.生态毒性^[12]

LC50：7.2mg/L（96h）（孔雀鱼）；0.97mg/L（48h）（水蚤）

2.生物降解性 暂无资料

3.非生物降解性^[13] 空气中，当羟基自由基浓度为5.00×10⁵个/cm³时，降解半衰期为2.5h（理论）。

当pH值为3.8，5.7，7.0，8.0时，水解半衰期分别为9min，6.5h，96h，405h。

4.生物富集性^[14] 金色圆腹雅罗鱼3d，BCF＜10；藻类1d，BCF约为170。

代森锌 MSDS

国标编号:
ＣＡＳ:	12122-67-7
中文名称:	代森锌
英文名称:	Dithane z-78；Ethylene bis(dithiocarbamato)zinc
别名:	乙撑双二硫代氨基甲酸锌
分子式:	C₄H₆N₂S₄Zn；(CH₂NHCSS)₂Zn
分子量:	275.75
熔点:
密度:	1.74
蒸汽压:	>100℃
溶解性:	不溶于水，不溶于多数有机溶剂
稳定性:	稳定
外观与性状:	灰白色粉末，工业品为淡黄色粉末，略带臭鸡蛋味，吸湿性强
危险标记:
用途:	用作硫化促进剂、农用杀菌剂，有65%及80%可湿性粉剂

2.对环境的影响
一、健康危害
侵入途径：吸入、食入。
健康危害：中毒主要影响中枢神经系统，对肝、肾有一定的损害。对皮肤和粘膜有刺激作用，可引起皮肤过敏。长期接触可能有引起甲状腺肿作用。
二、毒理学资料及环境行为
急性毒性：LD₅₀>5200mg/kg(大鼠经口)；LC₅₀1850mg/m³(大鼠吸入)；人经口5～g/kg(估计量)致死
其降解产物乙撑硫脲可引起试验鼠甲状腺肿大。
代森锌是有机硫杀菌剂，属低毒性。在1987～1988年，我们对不同厂家的制剂，在贮存过程中降解生成乙撑硫脲的变化，进行研究。结果表明，4种样品经16个月贮存，不论在开口或封口条件下，乙撑硫脲含量均随时间延长而增加。在贮存1个月后，乙撑硫脲含量就达到或超过允许标准。此外，乙撑硫脲不但易被植物吸收，输送到植物各部位，而且在土壤中淋溶程度也大。乙撑硫脲是一种潜在致甲状腺肿、致畸、致突变和在高剂量下致癌的化合物。
危险特性：遇明火、高热可燃。受热分解，放出氮、硫的氧化物等毒性气体。
燃烧(分解)产物：一氧化碳、二氧化碳、氮氧化物、硫化物、氧化锌。

3.现场应急监测方法

　

4.实验室监测方法

气相色谱法(蘑菇罐头)《农药残留量气相色谱法》国家商检局编

5.环境标准

前苏联(1976)	职业环境空气中最高容许浓度	0.5mg/m³(气溶胶)
前苏联(1978)	环境空气中最高容许浓度	0.01mg/m³(一次值) 0.006mg/m³(日均值)
前苏联(1978)	生活饮用水和娱乐用水水体中有害物质的最大允许浓度	0.03mg/L

6.应急处理处置方法
一、泄漏应急处理
切断火源。戴好防毒面具和手套。避免扬尘，小心扫起，置于袋中转移至安全场所。如大量泄漏，收集回收或载害处理后废弃。
二、防护措施
呼吸系统防护：高浓度环境中，建议佩戴供气式呼吸器。
眼睛防护：可采用安全面罩。
防护服：穿工作服。
手防护：必要时戴防护手套。
其它：注意个人清洁卫生。
三、急救措施
皮肤接触：脱去污染的衣着，用大量流动清水彻底冲洗。
眼睛接触：立即翻开上下眼睑，用流动清水或生理盐水冲洗。就医。
吸入：迅速脱离现场至空气新鲜处。保持呼吸道通畅。呼吸困难时给输氧。呼吸停止时，立即进行人工呼吸。就医。
食入：误服者给饮足量温水，催吐，就医。
灭火方法：泡沫、二氧化碳、干粉、砂土。