甲基叔丁基醚,1634-04-4，生产厂家，价格-洛克化工网移动版

返回



首页
客服小蜜
会员中心

基本信息

制备方法及用途

物化性质

安全信息

毒理性

MSDS

海关数据

结构与计算化学

上游产品

下游产品

表征图谱

甲基叔丁基醚

中文名称：: 甲基叔丁基醚

中文别名：: 甲基叔丁基醚;
2-甲氧基-2-甲基丙烷;
叔丁基甲基醚;
2-甲氧基-甲基丙烷;
叔丁基甲基醚MtBE;
叔丁基甲醚

英文名称：: Propane,2-methoxy-2-methyl-

英文别名：: methyl tert-butyl ether;
MTBE,Methyl tert-butyl ether;
MTB;
BOC-L-ARG(MTR)-OH;
Driveron;
tert-butyl-methyl-ether;
MTBE;
HP-MTBE;
MBT-ETHER;
tert-C4H9OCH3;
2-methoxy-2-methyl;
tert-BuOCH3;
Methyl tert-butyl ether;
ARCOPURE(R) MTBE;
tert-Butyl methyl ether

CAS No.：: 1634-04-4

分子式：: C₅H₁₂O

分子量：: 88.15

精确分子量：: 88.08880

PSA：: 9.23000

MDL：: MFCD00008812

EINECS：: 216-653-1

BRN：: 1730942

InChI：: InChI=1/C5H12O/c1-5(2,3)6-4/h1-4H33

危险品标志：: F:Highly flammable
Xi:Irritant

风险术语：: R11; R38;

安全术语：: S16; S33; S37;

分子结构式：

SDS：

甲基叔丁基醚制备方法及用途

制备方法

1.以混合丁烯和甲醇为原料，在酸性催化剂存在下，进行放热反应而得。具有代表性的工艺是德国赫斯和意大利斯纳姆普罗吉蒂法。美国化学研究、许可证公司和新化学公司开发的一种催化精馏新工艺已于1981年开始应用。此法把催化固定床反应器与蒸馏塔合于同一设备内，利用反应的释热于甲基叔丁基醚的蒸馏提纯，使过程的能耗降低。原料消耗定额：甲醇361kg/t、异丁烯（100%）650kg/t。2.以混合丁烯和甲醇为原料，在酸性催化剂存在下，进行放热反应而得。反应后的混合物经分离精制，把未反应的甲醇、C4馏分除去，得到一定纯度的甲基叔丁基醚。

合成制备方法

2.以混合丁烯和甲醇为原料，在酸性催化剂存在下，进行放热反应而得。反应后的混合物经分离精制，把未反应的甲醇、C4馏分除去，得到一定纯度的甲基叔丁基醚。

用途简介

该品主要用作汽油添加剂，具有优良的抗爆性。它与汽油的混溶性好，吸水少，对环境无污染。MTBE能改善汽油的冷起动特性和加速性能，对气阻没有不良影响。虽然甲基叔丁基醚热值低，但行车试验证明使用含10%MTBE的汽油能使燃料消耗下降7%，并使废气中含铅量、CO量特别是致癌多环芳烃的排放物明显降低。作为有机合成原料，可制高纯度的异丁烯。还可用于生产2-甲基丙烯醛、甲基丙烯酸及异戊二烯等。另外，还可用作分析溶剂、萃取剂。主要用作汽油添加剂，提高辛烷值，亦可裂解制得异丁烯。用作石蜡、香料、生物碱、树脂、天然及合成橡胶、脂肪物质的溶剂。一种优良的高辛烷值汽油添加剂和抗爆剂。甲基叔丁基醚作为无铅汽油添加剂，具有优良的抗爆性。它与汽油的混溶性好，吸水少，对环境无污染。试验证明，含10%MTBE的汽油能使燃料消耗下降7%，并使废气中含铅量、co量特别是致癌多环芳烃的排放物明显降低。另外，还可用作有机合成原料、萃取剂等。用作汽油添加剂。

用途

1.该品主要用作汽油添加剂，具有优良的抗爆性。它与汽油的混溶性好，吸水少，对环境无污染。MTBE能改善汽油的冷起动特性和加速性能，对气阻没有不良影响。虽然甲基叔丁基醚热值低，但行车试验证明使用含10%MTBE的汽油能使燃料消耗下降7%，并使废气中含铅量、CO量特别是致癌多环芳烃的排放物明显降低。作为有机合成原料，可制高纯度的异丁烯。还可用于生产2-甲基丙烯醛、甲基丙烯酸及异戊二烯等。另外，还可用作分析溶剂、萃取剂。主要用作汽油添加剂，提高辛烷值，亦可裂解制得异丁烯。用作石蜡、香料、生物碱、树脂、天然及合成橡胶、脂肪物质的溶剂。

2.一种优良的高辛烷值汽油添加剂和抗爆剂。甲基叔丁基醚作为无铅汽油添加剂，具有优良的抗爆性。它与汽油的混溶性好，吸水少，对环境无污染。试验证明，含10%MTBE的汽油能使燃料消耗下降7%，并使废气中含铅量、co量特别是致癌多环芳烃的排放物明显降低。另外，还可用作有机合成原料、萃取剂等。

3.用作汽油添加剂。^[23]

甲基叔丁基醚物化性质

外观与性状：: 透明液体
密度：: 0.7404
熔点：: -110 °C
沸点：: 55-56 °C(lit.)
闪点：: -27 °F
水溶解性：: 51 g/L (20 ºC)
折射率：: n20/D 1.369(lit.)
蒸汽压：: 251mmHg at 25°C
蒸汽密度：: 3.1 (vs air)
存储条件/存储方法：: 储存注意事项^[22] 储存于阴凉、通风的库房。远离火种、热源。库温不宜超过37℃。保持容器密封。应与氧化剂分开存放，切忌混储。采用防爆型照明、通风设施。禁止使用易产生火花的机械设备和工具。储区应备有泄漏应急处理设备和合适的收容材料。
稳定性相关：: 1.稳定性^[19] 稳定
2.禁配物^[20] 强氧化剂
3.聚合危害^[21] 不聚合
其它信息：: 1.性状：无色液体，具有醚样气味。^[1]
2.熔点（℃）：-108.6^[2]
3.沸点（℃）：55.2^[3]
4.相对密度（水=1）：0.74^[4]
5.相对蒸气密度（空气=1）：3.1^[5]
6.饱和蒸气压（kPa）：27（20℃）^[6]
7.燃烧热（kJ/mol）：-3360.7^[7]
8.临界压力（MPa）：3.4^[8]
9.辛醇/水分配系数：0.94~1.24^[9]
10.闪点（℃）：-34~-28^[10]
11.引燃温度（℃）：375^[11]
12.爆炸上限（%）：8^[12]
13.爆炸下限（%）：1^[13]
14.溶解性：不溶于水，易溶于乙醇、乙醚。^[14]
15.相对密度（20℃，4℃）：0.7406
16.常温折射率（n²⁰）：1.3690
17.常温折射率（n²⁵）：1.3663
18.偏心因子：0.267
19.溶度参数(J·cm^-3)^0.5：15.117
20.van der Waals面积（cm²·mol^-1）：9.080×10⁹
21.van der Waals体积（cm³·mol^-1）：61.710
22.气相标准燃烧热(焓)(kJ·mol^-1)：-3399.03
23.气相标准声称热(焓)( kJ·mol^-1) ：-283.47
24.气相标准熵(J·mol^-1·K^-1) ：357.8
25.气相标准生成自由能( kJ·mol^-1)：-117.45
26.液相标准燃烧热(焓)(kJ·mol^-1)：-3368.97
27.液相标准声称热(焓)( kJ·mol^-1)：-313.56
28.液相标准熵(J·mol^-1·K^-1) ：265.3
29.液相标准生成自由能( kJ·mol^-1)：-119.96
30.液相标准热熔(J·mol^-1·K^-1)：187.5

甲基叔丁基醚安全信息

包装等级：: II
风险类别：: 3
海关代码：: 2909199090
WGK_Germany：: 3
德国有关水污染物质的分类清单
危险类别码：: R11;R38
安全说明：: S9-S16-S24-S45-S36/37
RTECS号：: KN5250000
安全标志：: S22:不要吸入粉尘。
危险标志：: F:Flammable

甲基叔丁基醚毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KN5250000

CHEMICAL NAME :: Ether, tert-butyl methyl

CAS REGISTRY NUMBER :: 1634-04-4

BEILSTEIN REFERENCE NO. :: 1730942

LAST UPDATED :: 199712

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C5-H12-O

MOLECULAR WEIGHT :: 88.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-174603

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 23576 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB87-174603

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >148 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JSGRA2 Journal of Surgical Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1961- Volume(issue)/page/year: 53,572,1992

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 148 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JSGRA2 Journal of Surgical Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1961- Volume(issue)/page/year: 53,572,1992

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5960 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHHTAT Zhonghua Yixue Zazhi. Chinese Medical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1915- Suspended 1967-72. Volume(issue)/page/year: 70,172,1990

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 141 gm/m3/15M

TOXIC EFFECTS :: Behavioral - general anesthetic

REFERENCE :: ANESAV Anesthesiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1940- Volume(issue)/page/year: 11,455,1950

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1700 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHHTAT Zhonghua Yixue Zazhi. Chinese Medical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1915- Suspended 1967-72. Volume(issue)/page/year: 70,172,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 gm/kg/14D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(5),525,1990

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27 gm/kg/90D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - changes in calcium

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(5),525,1990

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1516 ppm/6H/10D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 143,301,1997 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 8000 ppm/6H

SEX/DURATION :: multigeneration

TOXIC EFFECTS :: Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 17(S1),S13,1997

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 4000 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 17(S1),S21,1997

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 8000 ppm/6H

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 17(S1),S21,1997 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 144 mg/m3 (40 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 100 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4267 No. of Facilities: 614 (estimated) No. of Industries: 6 No. of Occupations: 9 No. of Employees: 5996 (estimated) No. of Female Employees: 1783 (estimated)

毒理学数据：

1.急性毒性^[15]

LD50：4g/kg（大鼠经口）；＞7500mg/kg（兔经皮）

LC50：41000mg/m³（大鼠吸入，4h）

2.刺激性 暂无资料

生态数据：

1.生态毒性^[16]

LC50：110mg/L（96h）（黑头呆鱼）

EC50：11.4~55mg/L（5，15，30min）（发光菌，Microtox测试）

2.生物降解性^[17]

好氧生物降解（h）：672~4320

厌氧生物降解（h）：2688~17280

3.非生物降解性^[18]

空气中光氧化半衰期（h）：20.7~265

甲基叔丁基醚 MSDS

第一部分：化学品名称

甲基叔丁基醚海关数据

中国海关编码：2909199090

概述：: 2909199090. 其他无环醚及其卤化衍生物（包括磺化，硝化或亚硝化衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
申报要素：: 品名, 成分含量, 用途
摘要/Summary：: 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

甲基叔丁基醚分子结构与计算化学数据

分子结构数据

1、摩尔折射率：26.92

2、摩尔体积（cm³/mol）：117.4

3、等张比容（90.2K）：245.8

4、表面张力（dyne/cm）：19.1

5、极化率（10^-24cm³）：10.67

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:0

3.氢键受体数量:1

4.可旋转化学键数量:1

5.互变异构体数量:无

6.拓扑分子极性表面积9.2

7.重原子数量:6

8.表面电荷:0

9.复杂度:33.7

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

甲基叔丁基醚上游产品

对氯甲基苯甲酸叔丁醇碘甲烷甲醇异丁烯

甲基叔丁基醚下游产品

1-(1-butoxyethenoxy)butane 1,1,1,2,3,3,3-七氟代-2-三氟代甲基丙烷 1-tert-butoxy-2,2-dichloro-1,1,2-trifluoro-ethane 2-[difluoro(trifluoromethoxy)methyl]-1,1,1,2,3,3,3-heptafluoropropane 1-hydronona-fluoro-2-methylpropane